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We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2023-03-02 | Arthrobacter phage Bridgette [4303 multi-frame micrographs composed of 40 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-28016,8eci |
1.6 TB | 4.0 Å | |
2023-03-01 | CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine [10530 micrographs in MRC format] | Fay JF, Roth BL, Zhang S [Pubmed: 35835867] [DOI: 10.1038/s41594-022-00796-6] EMD-26599,7um7 |
924.6 GB | 2.75 Å | |
2023-03-01 | CryoEM structure of full-length dimeric ClbP [3888 multi-frame micrographs composed of 50 frames each in TIFF format] | Velilla JA, Walsh RM, Gaudet R [Pubmed: 36253550] [DOI: 10.1038/s41589-022-01142-z] EMD-26593,7ul6 |
1.1 TB | 3.73 Å | |
2023-02-28 | GroEL on Quantifoil grid [783 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-34743 |
128.4 GB | 2.81 Å | |
2023-02-28 | Cryo-ET tilt series of HPIV3 clinical isolates [11 tilt series in MRC format] | Marcink T, Porotto M, des Georges A, Moscona A [Pubmed: 36763666] [DOI: 10.1126/sciadv.ade2727] EMD-27550 |
33.7 GB | 10.2 Å | |
2023-02-28 | Cryo-ET tilt series of HPIV3 clinical isolates in the presence of an F neutralizing Fab [6 tilt series in MRC format] | Marcink T, Cheng W, Porotto M, des Georges A, Moscona A [Pubmed: 36763666] [DOI: 10.1126/sciadv.ade2727] EMD-27551 |
19.1 GB | 16.5 Å | |
2023-02-28 | Cryo pFIB/SEM of PEG beads (test sample) [193 micrographs in TIFF format] | Dumoux M, Glen T, Smith JLR, Ho EML, Perdigão LMA, Pennington A, Klumpe S, Yee NBY, Farmer DA, Lai PYA, Bowles W, Kelley R, Plitzko JM, Wu L, Basham M, Clare DK, Siebert CA, Darrow MC, Naismith JH, Grange M [Pubmed: 36805107] [DOI: 10.7554/elife.83623] |
5.3 GB | — | |
2023-02-28 | Cryo serial FIB SEM of mouse brain tissue [59 micrographs in TIFF format] | Dumoux M, Glen T, Smith JLR, Ho EML, Perdigão LMA, Pennington A, Klumpe S, Yee NBY, Farmer DA, Lai PYA, Bowles W, Kelley R, Plitzko JM, Wu L, Basham M, Clare DK, Siebert CA, Darrow MC, Naismith JH, Grange M [Pubmed: 36805107] [DOI: 10.7554/elife.83623] |
3.0 GB | — | |
2023-02-28 | Cryo serial FIB/SEM of HeLa cells [46 micrographs in TIFF format] | Dumoux M, Glen T, Smith JLR, Ho EML, Perdigão LMA, Pennington A, Klumpe S, Yee NBY, Farmer DA, Lai PYA, Bowles W, Kelley R, Plitzko JM, Wu L, Basham M, Clare DK, Siebert CA, Darrow MC, Naismith JH, Grange M [Pubmed: 36805107] [DOI: 10.7554/elife.83623] |
6.7 GB | — | |
2023-02-28 | Cryo serial FIB/SEM of mouse heart tissue [136 micrographs in TIFF format] | Dumoux M, Glen T, Smith JLR, Ho EML, Perdigão LMA, Pennington A, Klumpe S, Yee NBY, Farmer DA, Lai PYA, Bowles W, Kelley R, Plitzko JM, Wu L, Basham M, Clare DK, Siebert CA, Darrow MC, Naismith JH, Grange M [Pubmed: 36805107] [DOI: 10.7554/elife.83623] |
18.0 GB | — | |
2023-02-28 | Cryo serial FIB/SEM of RPE-1 cells [18 micrographs in TIFF format] | Dumoux M, Glen T, Smith JLR, Ho EML, Perdigão LMA, Pennington A, Klumpe S, Yee NBY, Farmer DA, Lai PYA, Bowles W, Kelley R, Plitzko JM, Wu L, Basham M, Clare DK, Siebert CA, Darrow MC, Naismith JH, Grange M [Pubmed: 36805107] [DOI: 10.7554/elife.83623] |
826.6 MB | — | |
2023-02-28 | GroEL on EG-grid stored for 3 months after graphene oxidation [1209 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-34106 |
217.8 GB | 2.06 Å | |
2023-02-28 | GroEL on EG-grid [531 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-31310 |
95.2 GB | 1.99 Å | |
2023-02-28 | GroEL on hydrophilized graphene grid (low particle density) [6149 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-31311 |
1.1 TB | 2.08 Å | |
2023-02-28 | Beta-galactosidase on EG-grid [3500 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-31313 |
369.6 GB | 1.81 Å | |
2023-02-28 | SARS-CoV-2 spike protein (1-up RBD) on EG-grid [1495 multi-frame micrographs composed of 60 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-32160 |
373.0 GB | 3.1 Å | |
2023-02-28 | SARS-CoV-2 spike protein (1-up RBD) on Quantifoil grid [2403 multi-frame micrographs composed of 60 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-32161 |
594.8 GB | 3.23 Å | |
2023-02-28 | Apoferritin on EG-grid [7500 multi-frame micrographs composed of 64 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-31314 |
841.1 GB | 1.29 Å | |
2023-02-28 | GroEL on hydrophilized graphene grid (high particle density) [700 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-32159 |
133.7 GB | 2.09 Å | |
2023-02-28 | GAPDH on EG-grid [270 multi-frame micrographs composed of 40 frames each in TIFF format] | Fujita J, Makino F, Asahara H, Moriguchi M, Kumano S, Anzai I, Kishikawa J, Matsuura Y, Kato T, Namba K, Inoue T [Pubmed: 36755111] [DOI: 10.1038/s41598-023-29396-0] EMD-32162 |
47.4 GB | 2.16 Å | |
2023-02-28 | Single particle cryo-EM dataset of mitochondrial respiratory complex I from Bos taurus in DDM [2370 multi-frame micrographs composed of 24 frames each in MRC format] | Bridges HR, Blaza JN, Yin Z, Chung I, Pollak MN, Hirst J [Pubmed: 36701435] [DOI: 10.1126/science.ade3332] EMD-14127,EMD-14126,EMD-14128,EMD-14129,EMD-14130,EMD-14131,7qsd |
352.7 GB | 2.8 - 3.5 Å | |
2023-02-28 | Single particle cryo-EM dataset of mitochondrial respiratory complex I from Bos taurus in DDM in the presence of IM1761092 [17203 multi-frame micrographs composed of 40 frames each in TIFF format] | Bridges HR, Blaza JN, Yin Z, Chung I, Pollak MN, Hirst J [Pubmed: 36701435] [DOI: 10.1126/science.ade3332] EMD-14251,EMD-14252,EMD-14253,EMD-14254,EMD-14255,EMD-14256,EMD-14257,EMD-14258,EMD-14259,EMD-14260,EMD-14261,EMD-14262,EMD-14263,EMD-14264,EMD-14265,EMD-14266,EMD-14267,EMD-14268,EMD-14269,EMD-14270,EMD-14272,EMD-14273,EMD-14274,EMD-14275,EMD-14276,EMD-14277,EMD-14278,EMD-14279,EMD-14280,EMD-14281,EMD-14282,EMD-14283,EMD-14284,EMD-14285,EMD-14286,EMD-14287,EMD-14288,EMD-14289,EMD-14290,EMD-14291,EMD-14292,EMD-14293,EMD-14294,EMD-14295,EMD-14296,EMD-14297,EMD-14298,EMD-14299,EMD-14300,EMD-14301,EMD-14302,EMD-14303,EMD-14304,EMD-14305,EMD-14306,EMD-14307,EMD-14308,EMD-14309,EMD-14310,EMD-14311,7r41,7r42,7r43,7r44,7r45,7r46,7r47,7r48,7r4c,7r4d,7r4f,7r4g |
6.5 TB | 2.17 - 2.68 Å | |
2023-02-27 | CryoEM micrographs of mouse apoferritin in a range of ice thicknesses on different microscope setups [multiple data sets in MRC and TIFF formats] | Neselu K, Wang B, Rice WJ, Potter CS, Carragher B, Chua EYD [Pubmed: 36742017] [DOI: 10.1016/j.yjsbx.2023.100085] EMD-29566,EMD-29567,EMD-29568,EMD-29569,EMD-29570,EMD-29573,EMD-29574,EMD-29575,EMD-29576,EMD-29577,EMD-29589,EMD-29591,EMD-29592,EMD-29593,EMD-29594,EMD-29554,EMD-29555,EMD-29556,EMD-29557,EMD-29558,EMD-29536,EMD-29535,EMD-29559,EMD-29513,EMD-29393 |
5.7 TB | 2.36 - 10.18 Å | |
2023-02-27 | Cryo-EM micrographs of full-length human BIRC6 dimer with a bound DIABLO (SMAC) homodimer [multiple data sets in EER format] | Ehrmann JF, Grabarczyk DB, Clausen T [Pubmed: 36758105] [DOI: 10.1126/science.ade8873] EMD-15675,8auw |
24.2 TB | 7.2 Å | |
2023-02-27 | Gordonia phage Cozz [2799 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-28018,8eck |
759.4 GB | 2.6 Å |