大阪大学のEMPIAR-PDBjチームでは、アジアの電顕研究者が、EMPIARデータベースに大きな電顕画像を転送するお手伝いをしています。 ネットワークでイギリスに転送する代わりに、ハードディスク自体を郵送・宅配便で大阪大学に送付、あるいは阪大のサーバまでネットワーク転送していただければ、こちらで仲介して登録サイトへの転送を代行します。 EMPIARへの登録を希望する方で、阪大へのデータ送付・転送をご希望の方は、まず、e-mail で、登録したい電顕画像データについて、ご相談ください。
Sars-CoV-2の構造が急速に決定され、EMDBやPDBに登録されています。これらは構造ベースの創薬の起点となるでしょう。 Cryo-EMのコミュニティで、これらのデータを検証し再解析を行えるようにするため、緊急のお願いをしたいと思います。 a)SARS-CoV-2に関するデータをEMDB(さらにPDB)に登録済みでしたら、その2D画像データを是非、EMPIARに登録してください。 b)SARS-CoV-2に関するデータの収集を行い、まだEMDBに未登録の方は、是非その画像データをEMPIARに登録してください。 CryoEMのコミュニティが画像処理とモデル構築を支援してくれるでしょう。
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2023-02-03 | Cryo-EM structure of human NKCC1 K289NA492E bound with bumetanide [4273 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao YZ [Pubmed: 35585053] [DOI: 10.1038/s41467-022-30407-3] EMD-24812,7s1y |
2.1 TB | 3.6 Å | |
2023-02-03 | Cryo-electron tomography on plasma FIB lamellae of HeLa cells [6481 tilt series in EER format] | Berger C, Dumoux M, Glen T, Neville NBY, Mitchels JM, Patáková Z, Darrow MC, Naismith JH, Grange M EMD-15636 |
622.2 GB | 4.9 Å | |
2023-02-01 | Cryo-EM data and 2DTM results of entire sections of differentiated ER-HoxB8 cells [multiple data sets in TIFF and MRC formats] | Elferich JE, Schiroli GS, Scadden DS, Grigorieff NG [Pubmed: 36382886] [DOI: 10.1101/2022.06.13.495969] |
1.3 TB | — | |
2023-02-01 | Human cytoplasmic dynein bound to Lis1 [multiple data sets in TIFF format] | Reimer JM, DeSantis ME, Reck-Peterson SL, Leschziner AE [Pubmed: 36692009] [DOI: 10.7554/eLife.84302] EMD-27783,EMD-27782,8dyv,8dyu |
983.3 GB | 3.97 - 4.0 Å | |
2023-02-01 | Cryo-EM data of alpha-synuclein A53T fibril [2663 micrographs in MRC format] | Wu KP, Huang JYC EMD-32636,7wnz |
233.8 GB | 3.4 Å | |
2023-02-01 | Mycobacterium phage Che8 [1203 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-27824,8e16 |
763.1 GB | 2.5 Å | |
2023-02-01 | Mycobacterium phage Bobi [1915 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-28015,8ec8 |
1.2 TB | 2.5 Å | |
2023-02-01 | CryoET tilt series of mouse sperm flagella after FIB-SEM milling [69 tilt series in MRC format] | Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Guo C, Yu Z, Lishko PV, Agard DA, Vale RD [Pubmed: 36593309] [DOI: 10.1038/s41594-022-00861-0] EMD-27444 |
194.0 GB | 25.0 Å | |
2023-02-01 | Single particle cryogenic electron micrographs of respiratory supercomplex I+III2 from Vigna radiata [multiple data sets in TIFF format] | Maldonado M, Letts JA [Pubmed: 36581760] [DOI: 10.1038/s41477-022-01306-8] EMD-27934,8e73 |
16.4 TB | 3.2 Å | |
2023-01-31 | Cryo-EM micrographs of APOBEC3G bound to HIV-1 Vif in comblex with CBF-beta and CUL5 E3 ligase [11803 multi-frame micrographs composed of 2051 frames each in EER format] | Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS [Pubmed: 36598981] [DOI: 10.1126/sciadv.ade3168] EMD-27875,EMD-27885,EMD-27887,8e40 |
11.4 TB | 3.57 - 5.4 Å | |
2023-01-31 | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease [9524 multi-frame micrographs composed of 40 frames each in TIFF format] | Ghanbarpour A, Fei X, Baker TA, Davis JH, Sauer RT EMD-28585,8et3 |
4.0 TB | 3.7 Å | |
2023-01-31 | PYD-106 bound human GluN1a-GluN2C NMDA receptor in the presence of D-cycloserine and glutamate [11714 multi-frame micrographs composed of 30 frames each in TIFF format] | Chou TH [Pubmed: 36309015] [DOI: 10.1016/j.molcel.2022.10.008] EMD-27955,EMD-27958,8e94,8e97 |
2.1 TB | 3.72 - 4.19 Å | |
2023-01-30 | Structure of RecT protein from Listeria innoccua phage A118 in complex with 83-mer annealed duplex [2038 multi-frame micrographs composed of 36 frames each in MRC format] | Bell CE [Pubmed: 36543802] [DOI: 10.1038/s41467-022-35572-z] EMD-26434,7ub2 |
1.6 TB | 3.4 Å | |
2023-01-30 | Single particle cryo-EM dataset for E. coli MlaFEDB bound to MlaC [multiple data sets in MRC and TIFF formats] | MacRae MR, Coudray N, Bhabha G, Ekiert DC EMD-29041 |
5.0 TB | 7.8 Å | |
2023-01-30 | Integration of an event-driven Timepix3 hydrid pixel detector into a cryo-EM workflow [multiple data sets in MRCS and TPX3 formats] | van Schayck JP, Zhang Y, Knoops K, Peters PJ, Ravelli RBG [Pubmed: 34342280] [DOI: 10.1107/S2059798321007233] EMD-15389,8aey |
2.7 TB | 3.05 Å | |
2023-01-30 | ChRmine in MSP1E3D1 lipid nanodisc [10903 multi-frame micrographs composed of 50 frames each in TIFF format] | Tucker K, Sridharan S, Adesnik H, Brohawn SG [Pubmed: 35977941] [DOI: 10.1038/s41467-022-32441-7] EMD-25091,EMD-25079,7sfk,7sfj |
7.0 TB | 2.74 Å | |
2023-01-30 | Translating 70S ribosome [19449 multi-frame micrographs composed of 1295 frames each in EER format] | Fromm SA, O'Connor KM, Purdy M, Bhatt PR, Loughran G, Atkins JF, Jomaa A, Mattei S EMD-15793,8b0x |
7.1 TB | 1.55 Å | |
2023-01-30 | Cryogenic electron tomographs of Coxsackievirus A9 [2421 multi-frame micrographs composed of 30 frames each in MRC format] | Domanska A, Plavec Z, Ruokolainen V, Löflund B, Marjomäki V, Butcher SJ [Pubmed: 36448797] [DOI: 10.1128/jvi.01367-22] EMD-15634,8at5 |
2.1 TB | 2.9 Å | |
2023-01-30 | 3D-surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semi-supervised deep learning [7 reconstructed volumes in MRC format] | Dyhr MCA, Sadeghi M, Moynova R, Knappe C, Kepsutlu Çakmak B, Werner S, Schneider G, McNally J, Noe F, Ewers H | 23.5 GB | — | |
2023-01-26 | Apo-ChRmine in MSP1E3D1 lipid nanodisc [5339 multi-frame micrographs composed of 50 frames each in TIFF format] | Tucker KCT, Brohawn SGB [Pubmed: 35977941] [DOI: 10.1038/s41467-022-32441-7] EMD-25135,7shs |
3.5 TB | 4.1 Å | |
2023-01-25 | Ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA [multiple data sets in TIFF format] | Lemonidis K, Rennie ML, Arkinson C, Chaugule VK, Clarke M, Streetley J, Walden H [Pubmed: 36385258] [DOI: 10.15252/embj.2022111898] EMD-14694,7zf1 |
2.9 TB | 4.14 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 3xTEL DNA template [6252 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27097,EMD-27099 |
1.5 TB | 3.61 - 3.62 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 6xTEL DNA template [8658 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27109 |
1.9 TB | 3.69 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 4xTEL-FB DNA template (PIC and advanced PIC) [7799 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27104,EMD-27107,8d0b,8d0k |
1.6 TB | 3.43 - 4.27 Å | |
2023-01-20 | Cryogenic electron tomographs of Coxsackievirus A9 treated with endosomal ionic condition buffer [1964 multi-frame micrographs composed of 30 frames each in MRC format] | Domanska A, Plavec Z, Ruokolainen V, Löflund B, Marjomäki V, Butcher SJ [Pubmed: 36448797] [DOI: 10.1128/jvi.01367-22] EMD-15706,8axx |
1.8 TB | 3.3 Å |