오사카 대학의 EMPIAR-PDBj 팀은, 아시아의 EM 연구자가 용량이 큰 EM 이미지를 EMPIAR 데이터베이스에 전송하는 것을 돕고 있습니다. 인터넷을 통하여 EBI (UK)에 직>접 데이터를 전송하는 대신, 이용자는 우편이나 택배를 통하여 하드 디스크를 오사카 대학으로 보내실 수 있습니다. 혹은 인터넷을 이용하여 오사카 대학의 서버로 전>송 하실 수 있습니다. 오사카 대학에 데이터 전송 서비스를 희망하시는 분은 데이터를 보내시기 전에 먼저 이메일 통하여 등록하시고 싶은 EM데이터에 관하여 상담하십시오.
Sars-CoV-2의 구조가 급속하게 결정되어, EMDB 및 PDB에 등록되고 있습니다. 이러한 정보는 구조 기반 신약 개발의 기점이 될 수 있습니다. Cryo-EM 커뮤니티에서는 이러한 데이터를 확인하고 다시 분석 할 수 있도록 다음과 같이 긴급히 부탁 드리고 있습니다. a) SARS-CoV-2에 대한 데이터를 EMDB (혹은 PDB)에 등록 하셨다면, 2D 이미지 데이터를 반드시 EMPIAR에 등록해 주십시오. b) SARS-CoV-2에 관한 데이터를 수집하고 구조를 등록하지 않으신 분은, Cryo-EM 커뮤니티가 이미지 처리 및 모델 구축을 지원할 수 있도록 EMPIAR에 이미지 데이터를 등록 하실 것을 고려해 주십시오.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2023-02-03 | Cryo-EM structure of human NKCC1 K289NA492E bound with bumetanide [4273 multi-frame micrographs composed of 40 frames each in TIFF format] | Zhao YZ [Pubmed: 35585053] [DOI: 10.1038/s41467-022-30407-3] EMD-24812,7s1y |
2.1 TB | 3.6 Å | |
2023-02-03 | Cryo-electron tomography on plasma FIB lamellae of HeLa cells [6481 tilt series in EER format] | Berger C, Dumoux M, Glen T, Neville NBY, Mitchels JM, Patáková Z, Darrow MC, Naismith JH, Grange M EMD-15636 |
622.2 GB | 4.9 Å | |
2023-02-01 | Cryo-EM data and 2DTM results of entire sections of differentiated ER-HoxB8 cells [multiple data sets in TIFF and MRC formats] | Elferich JE, Schiroli GS, Scadden DS, Grigorieff NG [Pubmed: 36382886] [DOI: 10.1101/2022.06.13.495969] |
1.3 TB | — | |
2023-02-01 | Human cytoplasmic dynein bound to Lis1 [multiple data sets in TIFF format] | Reimer JM, DeSantis ME, Reck-Peterson SL, Leschziner AE [Pubmed: 36692009] [DOI: 10.7554/eLife.84302] EMD-27783,EMD-27782,8dyv,8dyu |
983.3 GB | 3.97 - 4.0 Å | |
2023-02-01 | Cryo-EM data of alpha-synuclein A53T fibril [2663 micrographs in MRC format] | Wu KP, Huang JYC EMD-32636,7wnz |
233.8 GB | 3.4 Å | |
2023-02-01 | Mycobacterium phage Che8 [1203 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-27824,8e16 |
763.1 GB | 2.5 Å | |
2023-02-01 | Mycobacterium phage Bobi [1915 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-28015,8ec8 |
1.2 TB | 2.5 Å | |
2023-02-01 | CryoET tilt series of mouse sperm flagella after FIB-SEM milling [69 tilt series in MRC format] | Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Guo C, Yu Z, Lishko PV, Agard DA, Vale RD [Pubmed: 36593309] [DOI: 10.1038/s41594-022-00861-0] EMD-27444 |
194.0 GB | 25.0 Å | |
2023-02-01 | Single particle cryogenic electron micrographs of respiratory supercomplex I+III2 from Vigna radiata [multiple data sets in TIFF format] | Maldonado M, Letts JA [Pubmed: 36581760] [DOI: 10.1038/s41477-022-01306-8] EMD-27934,8e73 |
16.4 TB | 3.2 Å | |
2023-01-31 | Cryo-EM micrographs of APOBEC3G bound to HIV-1 Vif in comblex with CBF-beta and CUL5 E3 ligase [11803 multi-frame micrographs composed of 2051 frames each in EER format] | Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS [Pubmed: 36598981] [DOI: 10.1126/sciadv.ade3168] EMD-27875,EMD-27885,EMD-27887,8e40 |
11.4 TB | 3.57 - 5.4 Å | |
2023-01-31 | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease [9524 multi-frame micrographs composed of 40 frames each in TIFF format] | Ghanbarpour A, Fei X, Baker TA, Davis JH, Sauer RT EMD-28585,8et3 |
4.0 TB | 3.7 Å | |
2023-01-31 | PYD-106 bound human GluN1a-GluN2C NMDA receptor in the presence of D-cycloserine and glutamate [11714 multi-frame micrographs composed of 30 frames each in TIFF format] | Chou TH [Pubmed: 36309015] [DOI: 10.1016/j.molcel.2022.10.008] EMD-27955,EMD-27958,8e94,8e97 |
2.1 TB | 3.72 - 4.19 Å | |
2023-01-30 | Structure of RecT protein from Listeria innoccua phage A118 in complex with 83-mer annealed duplex [2038 multi-frame micrographs composed of 36 frames each in MRC format] | Bell CE [Pubmed: 36543802] [DOI: 10.1038/s41467-022-35572-z] EMD-26434,7ub2 |
1.6 TB | 3.4 Å | |
2023-01-30 | Single particle cryo-EM dataset for E. coli MlaFEDB bound to MlaC [multiple data sets in MRC and TIFF formats] | MacRae MR, Coudray N, Bhabha G, Ekiert DC EMD-29041 |
5.0 TB | 7.8 Å | |
2023-01-30 | Integration of an event-driven Timepix3 hydrid pixel detector into a cryo-EM workflow [multiple data sets in MRCS and TPX3 formats] | van Schayck JP, Zhang Y, Knoops K, Peters PJ, Ravelli RBG [Pubmed: 34342280] [DOI: 10.1107/S2059798321007233] EMD-15389,8aey |
2.7 TB | 3.05 Å | |
2023-01-30 | ChRmine in MSP1E3D1 lipid nanodisc [10903 multi-frame micrographs composed of 50 frames each in TIFF format] | Tucker K, Sridharan S, Adesnik H, Brohawn SG [Pubmed: 35977941] [DOI: 10.1038/s41467-022-32441-7] EMD-25091,EMD-25079,7sfk,7sfj |
7.0 TB | 2.74 Å | |
2023-01-30 | Translating 70S ribosome [19449 multi-frame micrographs composed of 1295 frames each in EER format] | Fromm SA, O'Connor KM, Purdy M, Bhatt PR, Loughran G, Atkins JF, Jomaa A, Mattei S EMD-15793,8b0x |
7.1 TB | 1.55 Å | |
2023-01-30 | Cryogenic electron tomographs of Coxsackievirus A9 [2421 multi-frame micrographs composed of 30 frames each in MRC format] | Domanska A, Plavec Z, Ruokolainen V, Löflund B, Marjomäki V, Butcher SJ [Pubmed: 36448797] [DOI: 10.1128/jvi.01367-22] EMD-15634,8at5 |
2.1 TB | 2.9 Å | |
2023-01-30 | 3D-surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semi-supervised deep learning [7 reconstructed volumes in MRC format] | Dyhr MCA, Sadeghi M, Moynova R, Knappe C, Kepsutlu Çakmak B, Werner S, Schneider G, McNally J, Noe F, Ewers H | 23.5 GB | — | |
2023-01-26 | Apo-ChRmine in MSP1E3D1 lipid nanodisc [5339 multi-frame micrographs composed of 50 frames each in TIFF format] | Tucker KCT, Brohawn SGB [Pubmed: 35977941] [DOI: 10.1038/s41467-022-32441-7] EMD-25135,7shs |
3.5 TB | 4.1 Å | |
2023-01-25 | Ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA [multiple data sets in TIFF format] | Lemonidis K, Rennie ML, Arkinson C, Chaugule VK, Clarke M, Streetley J, Walden H [Pubmed: 36385258] [DOI: 10.15252/embj.2022111898] EMD-14694,7zf1 |
2.9 TB | 4.14 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 3xTEL DNA template [6252 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27097,EMD-27099 |
1.5 TB | 3.61 - 3.62 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 6xTEL DNA template [8658 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27109 |
1.9 TB | 3.69 Å | |
2023-01-20 | Movies for human CST-Pola-primase bound to 4xTEL-FB DNA template (PIC and advanced PIC) [7799 multi-frame micrographs composed of 40 frames each in TIFF format] | He Q, Lin X, Chavez BL, Agrawal S, Lusk BL, Lim C [Pubmed: 35830881] [DOI: 10.1038/s41586-022-05040-1] EMD-27104,EMD-27107,8d0b,8d0k |
1.6 TB | 3.43 - 4.27 Å | |
2023-01-20 | Cryogenic electron tomographs of Coxsackievirus A9 treated with endosomal ionic condition buffer [1964 multi-frame micrographs composed of 30 frames each in MRC format] | Domanska A, Plavec Z, Ruokolainen V, Löflund B, Marjomäki V, Butcher SJ [Pubmed: 36448797] [DOI: 10.1128/jvi.01367-22] EMD-15706,8axx |
1.8 TB | 3.3 Å |