Electron Microscopy Public Image Archive
Electron Microscopy Public Image Archive
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The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
| Release date | Imageset | Title | Authors and references | Size | Resolution |
|---|---|---|---|---|---|
| 2023-04-11 |  |
Structure of human choline/ethanolamine phosphotransferase [3115 multi-frame micrographs composed of 32 frames each in TIFF format] | Qian H EMD-34379,8gyx |
1.4 TB | 3.7 Å |
| 2023-03-30 |  |
human ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.4/5 Spike [7254 multi-frame micrographs composed of 1092 frames each in EER format] | Ni D, Myasnikov A, Stahlberg S, Lau K EMD-15587,EMD-15588,8aqs |
4.1 TB | 2.92 Å |
| 2023-03-30 |  |
mouse ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.4/5 Spike [7989 multi-frame micrographs composed of 1092 frames each in EER format] | Ni D, Myasnikov A, Stahlberg S, Lau K EMD-15586,EMD-15592,8aqw |
4.4 TB | 2.92 - 3.3 Å |
| 2023-03-27 |  |
Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant deltaN6 (in vitro, pH 6.2) [4095 multi-frame micrographs composed of 28 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] EMD-15222,EMD-15223,8a7o,8a7p |
616.1 GB | 3.0 - 3.4 Å |
| 2023-03-27 |  |
Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant V27M (in vitro, pH 6.2) [611 multi-frame micrographs composed of 40 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] EMD-15224,8a7q |
92.7 GB | 2.8 Å |
| 2023-03-27 |  |
Cryo electron microscopy of beta-2-microglobulin amyloid fibrils for the variant D76N (in vitro, pH 6.2) [3849 multi-frame micrographs composed of 36 frames each in TIFF format] | Wilkinson M, Gallardo RU, Martinez RM, Guthertz N, So M, Aubrey LD, Radford SE, Ranson NA [Pubmed: 36864041] [DOI: 10.1038/s41467-023-36791-8] EMD-15225,EMD-15226,EMD-15227,8a7t |
575.5 GB | 3.0 - 4.1 Å |
| 2023-03-27 |  |
Cryo-EM structure of the ribosome/Sec61 translocon with a macrocyclic inhibitor KZR-8445 [multiple data sets in TIFF and MRC formats] | Rehan S EMD-14776,7zl3 |
12.9 TB | 3.2 Å |
| 2023-03-27 |  |
mouse ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.2.12.1 Spike [8046 multi-frame micrographs composed of 945 frames each in EER format] | Ni D, Myasnikov A, Stahlberg S, Lau K EMD-15584,EMD-15585,EMD-15591,8aqv |
4.0 TB | 2.89 - 3.03 Å |
| 2023-03-27 |  |
mouse ACE2 receptor bound to SARS-CoV-2 variant Beta Spike [5671 multi-frame micrographs composed of 40 frames each in MRC format] | Ni D, Myasnikov A, Stahlberg S, Lau K EMD-15541,EMD-15589,8aqt |
3.8 TB | 4.4 Å |
| 2023-03-22 |  |
Electron cryo-tomography data on the ER-mitochondria encounter structure in cryo-FIB milled yeast cells [multiple data sets in MRC and TIFF formats] | Wozny MR, Di Luca A, Morado DR, Picco A, Khaddaj R, Campomanes P, Ivanovic L, Hoffmann PC, Miller EA, Vanni S, Kukulski W [Pubmed: 37165187] [DOI: 10.1038/s41586-023-06050-3] EMD-15355 |
236.6 GB | — |
| 2023-03-17 |  |
FMC63 scFv in complex with soluble CD19 [multiple data sets in TIFF format] | Meyerson JR, He C [Pubmed: 36867678] [DOI: 10.1126/sciimmunol.adf1426] EMD-26719,7urv |
1.4 TB | 3.05 Å |
| 2023-03-17 |  |
SBFSEM imaging of Leishmania haptomonad-like cells attached to plastic [252 multi-frame micrographs composed of 1 frames each in MRC format] | Yanase R, Sunter JD | 33.6 GB | — |
| 2023-03-17 |  |
Serial section electron tomography of a Leishmania haptomonad on the stomodeal valve in the sand fly [670 multi-frame micrographs composed of 1 frames each in MRC format] | Yanase R, Sunter JD | 6.7 GB | — |
| 2023-03-17 |  |
Serial section electron tomography of a Leishmania haptomonad-like cell attached to plastic [718 multi-frame micrographs composed of 1 frames each in MRC format] | Yanase R, Sunter JD | 10.8 GB | — |
| 2023-03-16 |  |
HMP1/alpha-catenin binding with actin filaments [multiple data sets in TIFF and MRC formats] | Rangarajan ES, Smith EW, Izard T [Pubmed: 36539037] [DOI: 10.1016/j.jbc.2022.102817] EMD-26805,7uuw |
16.9 TB | 3.36 Å |
| 2023-03-16 |  |
SBFSEM imaging of Leishmania haptomonads on the stomodeal valve in the sand fly [400 multi-frame micrographs composed of 1 frames each in MRC format] | Yanase R, Sunter JD | 82.0 GB | — |
| 2023-03-15 |  |
Performing Correlative Light and Electron Microscopy to reveal the structural organization and location of alpha-synuclein aggregation hotspots inside the neuron. [multiple data sets in DM4 and TIFF formats] | Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova E, Berezhnov AV, De S, Peddie C, Athauda D, Viridi GS, Zhang W, Evans JR, Wernick A, Zanjani ZS, Angelova PR, Esteras N, Vinikurov A, Morris K, Jeacock K, Tosatto L, Little D, Gissen P, Collinson L, Clarke DJ, Kunath T, Klenerman D, Abramov AY, Horrocks MH, Gandhi S S-BIAD465 |
88.4 GB | — |
| 2023-03-14 |  |
LRRC8A-BRIL:C Heteromer in lipid nanodiscs [multiple data sets in TIFF and MRCS formats] | Kern DM, Brohawn SG [Pubmed: 36928458] [DOI: 10.1038/s41594-023-00944-6] EMD-27686,EMD-27687,8ds9,8dsa |
2.4 TB | 3.17 - 3.48 Å |
| 2023-03-14 |  |
LRRC8A-BRIL(T48D):C Heteromer in GDN [multiple data sets in TIFF and MRCS formats] | Kern DM, Brohawn SG [Pubmed: 36928458] [DOI: 10.1038/s41594-023-00944-6] EMD-28898,EMD-28901,EMD-28903,EMD-28904,EMD-28905,EMD-28897,EMD-28894,EMD-28895,8f79,8f7b,8f7d,8f7e,8f7j,8f77,8f74,8f75 |
2.1 TB | 3.1 - 4.32 Å |
| 2023-03-13 |  |
mouse ACE2 receptor bound to SARS-CoV-2 variant Omicron BA.1 Spike [20892 multi-frame micrographs composed of 1568 frames each in EER format] | Ni D, Myasnikov A, Stahlberg S, Lau K EMD-15580,EMD-15581,EMD-15590,8aqu |
10.6 TB | 3.03 - 3.22 Å |
| 2023-03-13 |  |
FIB-SEM images about Control/OPA1 KD NIH-3T3 cells [1984 multi-frame micrographs composed of 1 frames each in TIFF format] | Suga S, Nakamura K, Kawai H, Hirabayashi Y | 46.8 GB | — |
| 2023-03-13 |  |
Tilt series of authentic mumps virus nucleocapsid isolated from lysate of chronically infected HeLa cells under arsenite stress [840 tilt series in TIFF format] | Zhang X, Mahamid J EMD-13133,EMD-13136,7ozr |
27.9 GB | 4.5 - 6.3 Å |
| 2023-03-03 |  |
Cryo-iDPC-STEM structure of TMV - convergence semi-angle 4.0 mrad [multiple data sets in TIFF format] | Lazić I, Wirix M, Leidl ML, Sachse C [Pubmed: 36064775] [DOI: 10.1038/s41592-022-01586-0] EMD-13781,7q2r |
1.2 GB | 3.5 Å |
| 2023-03-02 |  |
Gordonia phage Ziko [5058 multi-frame micrographs composed of 30 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-27992,8eb4 |
1.4 TB | 2.6 Å |
| 2023-03-02 |  |
Mycobacterium phage Cain [4638 multi-frame micrographs composed of 50 frames each in TIFF format] | Podgorski JM [Pubmed: 36649709] [DOI: 10.1016/j.str.2022.12.012] EMD-28017,8ecj |
1.5 TB | 2.9 Å |
