The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2021-09-22 | Oligo nucleosome fraction from metaphase chromosome in Xenopus egg extract lot2 [1456 multi-frame micrographs composed of 50 frames each in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] EMD-23821,EMD-23822 |
696.5 GB | 3.77 - 4.32 Å | |
2021-09-22 | Oligo nucleosome fraction from interphase chromosome in Xenopus egg extract lot2 [1376 multi-frame micrographs composed of 50 frames each in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] EMD-23819,EMD-23820 |
648.2 GB | 3.54 - 4.42 Å | |
2021-09-22 | Open linker DNA nucleosome reconstituted with GUB DNA [1576 multi-frame micrographs composed of 50 frames each in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] EMD-23824 |
777.0 GB | 4.52 Å | |
2021-09-22 | Closed linker DNA nucleosome reconstituted with GUB DNA [1320 multi-frame micrographs composed of 50 frames each in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] EMD-23823 |
624.4 GB | 3.77 Å | |
2021-09-24 | 'Freed' nucleosome isolated from non-crosslinked interphase chromosome in Xenopus egg extract lot2 [multiple data sets in TIFF format] | Arimura YA, Funabiki HF [Pubmed: 34478647] [DOI: 10.1016/j.molcel.2021.08.010] EMD-23826 |
1.1 TB | 5.44 Å | |
2021-11-16 | The cryo-EM structure of the CENP-A nucleosome in complex with the phosphorylated CENP-C: CENP-A nucleosome in complex with phosphorylated CENP-C C-terminal domain (601-864) and CENP-N N-terminal domain (1-211) [8017 multi-frame micrographs composed of 50 frames each in TIFF format] | Ariyoshi M, Makino F, Watanabe R, Nakagawa R, Kato T, Namba K, Arimura Y, Fujita R, Kurumizaka H, Okumura EI, Hara M, Fukagawa T [Pubmed: 33463726] [DOI: 10.15252/embj.2020105671] EMD-30239,EMD-30241,7by0 |
1.6 TB | 4.5 - 7.8 Å | |
2021-11-16 | The cryo-EM structure of the CENP-A nucleosome in complex with the phosphorylated CENP-C:: CENP-A nucleosome in complex with phosphorylated CENP-C C-terminal domain(601-864) [6533 multi-frame micrographs composed of 50 frames each in TIFF format] | Ariyoshi M, Makino F, Watanabe R, Nakagawa R, Kato T, Namba K, Arimura Y, Fujita R, Kurumizaka H, Okumura EI, Hara M, Fukagawa T [Pubmed: 33463726] [DOI: 10.15252/embj.2020105671] EMD-30240 |
1.4 TB | 6.8 Å | |
2021-11-16 | The cryo-EM structure of the CENP-A nucleosome in complex with the phosphorylated CENP-C:: CENP-A nucleosome in complex with CENP-C motif (655-675) and CENP-N N-terminal domain (1-211) [4630 multi-frame micrographs composed of 50 frames each in TIFF format] | Ariyoshi M, Makino F, Watanabe R, Nakagawa R, Kato T, Namba K, Arimura Y, Fujita R, Kurumizaka H, Okumura EI, Hara M, Fukagawa T [Pubmed: 33463726] [DOI: 10.15252/embj.2020105671] EMD-30237,7bxt |
1.3 TB | 4.2 Å | |
2020-09-11 | Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome [719 multi-frame micrographs composed of 30 frames each in MRCS format] | Armache J-P, Gamarra N, Johnson SL, Leonard JD, Wu S, Narlikar G, Cheng Y [Pubmed: 31210637] [DOI: 10.7554/eLife.46057] EMD-9352 |
1.4 TB | 3.39 Å | |
2022-06-20 | Cryo-EM data used for the determination of the structures of LACV-L in 3 different states: replication initiation state, transcription capped primer active site entry state and transcription initiation state [14341 multi-frame micrographs composed of 40 frames each in TIFF format] | Arragain B, Durieux Trouilleton Q, Baudin F, Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H [Pubmed: 35173159] [DOI: 10.1038/s41467-022-28428-z] EMD-13043,EMD-13040,EMD-13041,7orn,7ork,7orl |
2.2 TB | 2.8 - 3.6 Å | |
2022-05-24 | Cryo-EM data used for the determination of LACV-L structure in transcription early-elongation state [2510 multi-frame micrographs composed of 60 frames each in TIFF format] | Arragain B, Durieux Trouilleton Q, Baudin F, Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H [Pubmed: 35173159] [DOI: 10.1038/s41467-022-28428-z] EMD-13042,7orm |
721.4 GB | 3.3 Å | |
2022-01-24 | Structure of pathological TDP-43 filaments from ALS with FTLD (Individual 1, frontal cortex) [22896 multi-frame micrographs composed of 40 frames each in TIFF format] | Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Ryskeldi-Falcon B [Pubmed: 34880495] [DOI: 10.1038/s41586-021-04199-3] EMD-13708,7py2 |
3.9 TB | 2.59 Å | |
2022-01-21 | Structure of pathological TDP-43 filaments from ALS with FTLD (Individual 1, motor cortex) [12245 multi-frame micrographs composed of 40 frames each in TIFF format] | Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Ryskeldi-Falcon B [Pubmed: 34880495] [DOI: 10.1038/s41586-021-04199-3] EMD-13710 |
2.0 TB | 2.94 Å | |
2022-01-24 | Structure of pathological TDP-43 filaments from ALS with FTLD (Individual 2, frontal cortex) [15991 multi-frame micrographs composed of 41 frames each in TIFF format] | Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Ryskeldi-Falcon B [Pubmed: 34880495] [DOI: 10.1038/s41586-021-04199-3] EMD-13710 |
2.9 TB | 2.94 Å | |
2021-02-10 | Cryo-EM structure of K+-bound hERG channel [1496 multi-frame micrographs composed of 50 frames each in TIFF format] | Asai T, Adachi N, Moriya T, Kawasaki M, Suzuki K, Senda T, Murata T [Pubmed: 33450182] [DOI: 10.1016/j.str.2020.12.007] EMD-30412,7cn0 |
1.4 TB | 3.9 Å | |
2021-02-10 | Cryo-EM structure of K+-bound hERG channel in the presence of astemizole [1865 multi-frame micrographs composed of 50 frames each in TIFF format] | Asai T, Adachi N, Moriya T, Kawasaki M, Suzuki K, Senda T, Murata T [Pubmed: 33450182] [DOI: 10.1016/j.str.2020.12.007] EMD-30413,7cn1 |
1.8 TB | 3.7 Å | |
2022-06-13 | Structure of bile acid transporter NTCP [multiple data sets in TIFF format] | Asami J, Shimizu T, Ohto U [Pubmed: 35580629] [DOI: 10.1038/s41586-022-04845-4] EMD-31837,EMD-31838,EMD-31839,EMD-31840,EMD-32759,7vad,7vae,7vaf,7vag,7wsi |
8.6 TB | 3.11 - 3.55 Å | |
2022-04-06 | CryoEM Structure of the, UND-PP bound, WaaL O-Antigen Ligase [2378 multi-frame micrographs composed of 50 frames each in MRC format] | Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F [Pubmed: 35388216] [DOI: 10.1038/s41586-022-04555-x] EMD-26054,7tpg |
477.2 GB | 3.23 Å | |
2018-01-22 | Human TRPM4 ion channel in a lipid nanodisc in a calcium-free state [stack of 45247 particles in MRCS format] | Autzen HE, Myasnikov AG, Campbell MG, Asarnow D, Julius D, Cheng Y [Pubmed: 29217581] [DOI: 10.1126/science.aar4510] EMD-7132,6bqr |
162.5 GB | 3.2 Å | |
2018-01-22 | Human TRPM4 ion channel in a lipid nanodisc in a calcium-bound state [stack of 221100 particles in MRCS format] | Autzen HE, Myasnikov AG, Campbell MG, Asarnow D, Julius D, Cheng Y [Pubmed: 29217581] [DOI: 10.1126/science.aar4510] EMD-7133,6bqv |
84.4 GB | 3.1 Å | |
2021-12-14 | Identifying long-range synaptic inputs using genetically encoded labels and volume electron microscopy [6 multi-frame micrographs composed of 1 frames each in TIFF format] | Ayuso-Jimeno IP, Ronchi P, Wang T, Gallori CE, Gross CT [Pubmed: 35715545] [DOI: 10.1038/s41598-022-14309-4] |
68.7 GB | — | |
2021-01-29 | Single-particle cryo-EM dataset of the complex between a nucleosome and the regulatory linker of ALC1 [multiple data sets in TIFF and MRCS formats] | Bacic L, Gaullier G, Deindl S [Pubmed: 33357431] [DOI: 10.1016/j.celrep.2020.108529] EMD-11220,EMD-11221,6zhx,6zhy |
6.8 TB | 2.5 - 3.0 Å | |
2013-07-06 | S.cereviseae 80S ribosome direct electron detetector dataset [260 multi-frame micrographs composed of 16 frames each in MRCS format] | Bai XC, Fernandez IS, McMullan G, Scheres SH [Pubmed: 23427024] [DOI: 10.7554/eLife.00461] EMD-2275 |
260.0 GB | 4.5 Å | |
2018-06-20 | An atomic structure of human gamma-secretase [2925 multi-frame micrographs composed of 20 frames each in MRCS format] | Bai XC, Yan C, Yang G, Lu P, Ma D, Sun L, Zhou R, Scheres SHW, Shi Y [Pubmed: 26280335] [DOI: 10.1038/NATURE14892] EMD-3061,5a63 |
11.7 TB | 3.4 Å | |
2022-07-27 | Apoferritin structure at 1.46 angstrom resolution by CryoARM300II equipped with Apollo [7000 multi-frame micrographs composed of 24 frames each in TIFF format] | Bammes B, Spilman M, Sakamoto M, Fukumura T, Konyuba Y, Okunish E EMD-33707 |
1.1 TB | 1.47 Å |