The EMPIAR-PDBj team at Osaka University assists Asian EM researchers with the transfer of big EM image data to EMPIAR. Instead of sending the data directly to the EBI (UK) via the internet, hard drives can also be sent to Osaka University by postal mail or via a courier service. As an alternative, internet transfer to our server in Osaka is also available. If you would like to take advantage of our submission services, please contact us first by e-mail before sending the data to us.
We have seen a large number of SARS-CoV-2 structures being determined rapidly and deposited into the PDB and EMDB, which provides a starting point for structure-guided drug discovery. In order to validate and reanalyze the data by the cryo-EM community, we would like to make the following urgent appeal. a) If you have deposited any cryo-EM structures related to SARS-CoV-2 to the EMDB (and possibly the PDB), please deposit the raw data to EMPIAR. b) If you have collected cryo-EM data related to SARS-CoV-2 but have not yet deposited a structure, please consider depositing the raw data to EMPIAR, so that the cryo-EM community could contribute to processing and model-building.
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2024-03-25 | Cryo electron microscopy of quinol-dependent Nitric Oxide Reductase (qNOR) from Alcaligenes xylosoxidans [5466 multi-frame micrographs composed of 43 frames each in EER format] | Flynn AJ, Antonyuk SV, Eady RR, Muench SP, Hasnain SS [Pubmed: 37296134] [DOI: 10.1038/s41467-023-39140-x] |
738.4 GB | 2.2 Å | |
2024-03-20 | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex [592 micrographs in MRC format] | Pennington LF, Gasser P, Kleinboelting S, Zhang C, Skiniotis G, Eggel A, Jardetzky TS [Pubmed: 34862384] [DOI: 10.1038/s41467-021-27397-z] |
52.0 GB | 7.29 Å | |
2024-03-22 | Single-particle cryo-EM unaligned micrographs of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein [9221 multi-frame micrographs composed of 50 frames each in TIFF format] | Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem ER, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair MS, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L [Pubmed: 33789084] [DOI: 10.1016/j.chom.2021.03.005] |
2.4 TB | 3.9 Å | |
2024-03-26 | Cryo-EM micrographs of engineered encapsulin P3P4 [multiple data sets in MRC and MRCS formats] | Satler T, Jerala R | 69.3 GB | 3.1 Å | |
2024-03-19 | Unveiling the ultrastructural landscape of extracellular matrix via lift-out cryo-FIBSEM and cryo-ET [multiple data sets in TIFF and MRC formats] | Zens B., Fäßler F., Hansen J.M., Hauschild R., Datler J., Hodirnau V.V., Zheden V., Alanko J., Sixt M., Schur F.K.M. [DOI: 10.1083/jcb.202309125] |
183.0 GB | — | |
2024-02-29 | cryo-EM structure of rMRP2 in complex with probenecid [13827 multi-frame micrographs composed of 40 frames each in TIFF format] | Mazza TM, Roumeliotis TIR, Garitta EG, Drew DD, Rashid STR, Indiveri CI, Linton KJL, Choudhary JSC, Beis KB | 1.9 TB | 3.45 Å | |
2024-02-29 | cryo-EM structure of nucleotide-free rMRP2 [12785 multi-frame micrographs composed of 50 frames each in TIFF format] | Mazza TM, Roumeliotis TIR, Garitta EG, Drew DD, Rashid STR, Indiveri CI, Linton KJL, Choudhary JSC, Beis KB | 2.0 TB | 3.21 Å | |
2024-03-22 | Structural basis for directional rotation of the Salmonella flagellum [39332 multi-frame micrographs composed of 50 frames each in TIFF format] | Singh PK, Iverson TM | 9.0 TB | 3.4 - 6.7 Å | |
2024-02-28 | Sulfolobus acidocaldarius s-layer SlaA cryoET dataset [multiple data sets in MRC format] | Gambelli L, McLaren MJ, Sanders K, Gaines M, Clark L, Gold VAM, Kattnig D, Sikora M, Hanus C, Isupov M, Daum B [Pubmed: 38251732] [DOI: 10.7554/eLife.84617] |
945.1 GB | 11.2 Å | |
2024-03-21 | Single particle Cryo EM of the C-terminal half LRRK2 I2020T mutant bound to GZD-824 [8386 multi-frame micrographs composed of 50 frames each in EER format] | Villagran Suarez A, Leschziner A [Pubmed: 38039358] [DOI: 10.1126/sciadv.adk6191] |
7.4 TB | 3.1 Å | |
2024-03-20 | Cryo-electron microscopy Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex [multiple data sets in TIFF format] | Xing C, Zhuang Y, Xu TH, Feng Z, Zhou XE, Chen M, Wang L, Meng X, Xue Y, Wang J, Liu H, McGuire TF, Zhao G, Melcher K, Zhang C, Xu HE, Xie XQ [Pubmed: 32004460] [DOI: 10.1016/j.cell.2020.01.007] |
2.5 TB | 3.2 Å | |
2024-03-26 | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a tetrameric form [17529 multi-frame micrographs composed of 75 frames each in TIFF format] | Wang FW [Pubmed: 37040767] [DOI: 10.1016/j.str.2023.03.010] |
7.6 TB | 3.5 Å | |
2024-02-06 | Human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif [multiple data sets in TIFF and DM4 formats] | Muckenfuss LM, Jinek M [Pubmed: 29358758] [DOI: 10.1038/s41594-017-0020-6] |
1.2 TB | 3.07 Å | |
2024-02-16 | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form [13094 multi-frame micrographs composed of 75 frames each in TIFF format] | Wang FW [Pubmed: 37040767] [DOI: 10.1016/j.str.2023.03.010] |
7.0 TB | 2.66 - 2.8 Å | |
2024-02-08 | Single-particle cryo-EM unaligned micrographs of prefusion SARS-CoV-2 spike omicron B.1.1.529 variant [13697 multi-frame micrographs composed of 50 frames each in TIFF format] | Cerutti G, Guo Y, Liu L, Liu L, Zhang Z, Luo Y, Huang Y, Wang HH, Ho DD, Sheng Z, Shapiro L [Pubmed: 35172173] [DOI: 10.1016/j.celrep.2022.110428] |
3.4 TB | 3.11 Å | |
2024-02-09 | Single particle Cryo EM of the C-terminal half LRRK2 G2019S mutant bound to GZD-824 [7988 multi-frame micrographs composed of 40 frames each in EER format] | Villagran Suarez A, Leschziner A [Pubmed: 38039358] [DOI: 10.1126/sciadv.adk6191] |
7.0 TB | 2.99 Å | |
2024-02-08 | Single particle Cryo EM of the LRRK2 I2020T mutant bound to GZD-824 [4102 multi-frame micrographs composed of 40 frames each in EER format] | Villagran Suarez A, Leschziner A [Pubmed: 38039358] [DOI: 10.1126/sciadv.adk6191] |
4.6 TB | 3.4 Å | |
2024-02-06 | Single-particle cryo-EM unaligned micrographs of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein [7711 multi-frame micrographs composed of 50 frames each in TIFF format] | Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem ER, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair MS, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L [Pubmed: 33789084] [DOI: 10.1016/j.chom.2021.03.005] |
2.0 TB | 2.97 Å | |
2024-03-26 | Cryo-EM structure of mouse heavy-chain apoferritin [9846 multi-frame micrographs composed of 357 frames each in EER format] | Nazarov S.U., Myasnikov A.G., Mohammed I. | 963.4 GB | 1.09 Å | |
2024-02-06 | CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism [stack of 11404 particles in MRC format] | Xu M, Pintilie G, Liu Y, Chiu W, Maduke M | 1.2 TB | 2.46 Å | |
2024-02-06 | CryoEM structures of the human CLC-2-AK42 voltage gated chloride channel reveal a ball and chain gating mechanism [stack of 11498 particles in MRC format] | Xu M, Pintilie G, Liu Y, Chiu W, Maduke M | 1.2 TB | 2.46 Å | |
2024-02-06 | Raw micrographs of Form1-N2 peptide nanotube [7917 multi-frame micrographs composed of 40 frames each in TIFF format] | Wang F, Gnewou O, Conticello VP, Egelman EH [Pubmed: 35133794] [DOI: 10.1021/acs.chemrev.1c00753] |
1.8 TB | 3.4 Å | |
2024-02-16 | Cryo-EM reconstruction of the influenza A virus helical ribonucleoprotein-like [26515 multi-frame micrographs composed of 40 frames each in TIFF format] | Chenavier F, Ruigrok RWH, Schoehn G, Ballandras-Colas A, Crépin T [Pubmed: 38100595] [DOI: 10.1126/sciadv.adj9974] |
9.5 TB | 5.3 - 8.7 Å | |
2024-02-06 | Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein [2735 multi-frame micrographs composed of 50 frames each in TIFF format] | Cerutti G, Rapp M, Guo Y, Bahna F, Bimela J, Reddem ER, Yu J, Wang P, Liu L, Huang Y, Ho DD, Kwong PD, Sheng Z, Shapiro L [Pubmed: 34111408] [DOI: 10.1016/j.str.2021.05.014] |
746.5 GB | 3.42 Å | |
2024-03-26 | cryo-EM 3D maps of the S. cerevisiae Yta7 bound to the reconstituted nucleosome [16532 multi-frame micrographs composed of 75 frames each in TIFF format] | Wang FW [Pubmed: 36592926] [DOI: 10.1016/j.jbc.2022.102852] |
8.4 TB | 10.0 Å |