大阪大學的EMPIAR-PDBj團隊為亞洲EM研究人員向EMPIAR傳送大型EM圖像數據提供服務。 除了通過互聯網將數據直接傳送到EBI(UK),研究人員還可以通過郵政或快遞服務將數據硬盤發送到大阪大學,或者通過互聯網傳送到設置於大阪大學的服務器,然後由我們代為傳送至數據登錄網站。 如果您想使用此項服務,請先通過 電子郵件 與我們聯繫。
目前,大量的SARS-CoV-2相關結構已經被迅速確定並登錄到PDB和EMDB,這為以結構為基礎的藥物開發提供了起點。 為了方便Cryo-EM社團對數據進行驗證以及重新解析,我們謹發出以下緊急呼籲: a)如果您已經在EMDB(PDB)登錄了SARS-CoV-2相關的任何冷凍EM結構,請在EMPIAR登錄原始數據。 b)如果您已經收集了與SARS-CoV-2相關的cryo-EM數據但尚未登錄,請考慮在EMPIAR登錄原始數據,以便Cryo-EM社團能夠為處理和模型構建提供幫助。
Release date | Imageset | Title | Authors and references | Size | Resolution |
---|---|---|---|---|---|
2023-10-13 | SBF-SEM micrographs of A. algerae microsporidia spores, 45 min germination [300 micrographs in TIFF format] | Davydov A, Jaroenlak P, Ekiert D, Bhabha G [DOI: 10.7554/eLife.86638.1] |
55.9 GB | — | |
2023-10-13 | Single-particle cryo-EM of APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB-NTD [25837 multi-frame micrographs composed of 39 frames each in TIFF format] | Bodrug T, Welsh KA, Bolhuis DL, Paulаkonis E, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG [Pubmed: 37735619] [DOI: 10.1038/s41594-023-01105-5] |
22.8 TB | 3.5 Å | |
2023-10-13 | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate [multiple data sets in TIFF format] | Rüttermann MR, Koci MK, Lill PL, Geladas EDG, Kaschani FK, Klink BUK, Erdmann RE, Gatsogiannis CG [Pubmed: 37741838] [DOI: 10.1038/s41467-023-41640-9] |
4.9 TB | 4.1 - 4.7 Å | |
2023-10-13 | CryoEM micrographs collected on a RAD51-ATP-dsDNA filament sample [3850 multi-frame micrographs composed of 40 frames each in TIFF format] | Appleby R, Bollschweiler D, Chirgadze DY, Joudeh L, Pellegrini L [Pubmed: 37216117] [DOI: 10.1016/j.isci.2023.106689] |
960.3 GB | 2.9 Å | |
2023-10-10 | SBF-SEM micrographs of A. algerae spores, Ungerminated [250 micrographs in TIFF format] | Jaroenlak P, Cammer M, Davydov A, Sall J, Usmani M, Liang F, Ekiert D, Bhabha G [Pubmed: 32946515] [DOI: 10.1371/journal.ppat.1008738] |
46.6 GB | — | |
2023-10-10 | EM ladder: four-species cryoEM protein mix for workflow and algorithm benchmarking: Apoferritin, beta-galactosidase, PP7 VLPs and TMV [1862 micrographs in MRC format] | Bobe D, Eng E, Kopylov M | 98.7 GB | 2.38 - 3.36 Å | |
2023-10-09 | Cryo-EM SPA datasets for Antibodies 12-16 & 12-19 in complex with prefusion SARS-CoV-2 Spike glycoprotein (K3 movies/.tif files) [multiple data sets in TIFF format] | Casner RG, Shapiro L [Pubmed: 37776849] [DOI: 10.1016/j.immuni.2023.09.003] |
2.6 TB | 3.03 - 3.09 Å | |
2023-10-09 | Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network [multiple data sets in TIFF format] | Lee RG, Rudler DL, Raven SA, Peng L, Chopin A, Moh ESX, McCubbin T, Siira SJ, Fagan SV, DeBono NJ, Stentenbach M, Browne J, Rackham FF, Li J, Simpson KJ, Marcellin E, Packer NH, Reid GE, Padman BS, Rackham O, Filipovska A | 434.2 GB | — | |
2023-10-06 | CryoEM micrographs collected on a RAD51-ADP filament sample [9214 multi-frame micrographs composed of 50 frames each in TIFF format] | Appleby R, Bollschweiler D, Chirgadze DY, Joudeh L, Pellegrini L [Pubmed: 37216117] [DOI: 10.1016/j.isci.2023.106689] |
1.5 TB | 3.6 Å | |
2023-10-06 | Extracellular filaments of Pyrobaculum calidifontis [18019 multi-frame micrographs composed of 40 frames each in TIFF format] | Cvirkaite-Krupovic V, Egelman EH, Krupovic M, Wang F [Pubmed: 35727984] [DOI: 10.1073/pnas.2207037119] |
3.7 TB | 3.8 - 4.1 Å | |
2023-10-06 | Atypical flagella assembly and haploid genome coiling during male gamete formation in Plasmodium [multiple data sets in MRC format] | Hair M [DOI: 10.1101/2023.05.17.540968] |
100.7 GB | — | |
2023-10-03 | Single particle cryo-EM dataset of mouse mitochondrial complex I in the active state [1235 multi-frame micrographs composed of 25 frames each in MRC format] | Agip AA, Blaza JN, Bridges HR, Hirst J [Pubmed: 33067417] [DOI: 10.1038/s41467-020-18950-3] |
179.6 GB | 3.1 - 3.3 Å | |
2023-10-03 | Single particle cryo-EM dataset of bovine complex I in the deactive state [2988 multi-frame micrographs composed of 20 frames each in MRC format] | Blaza JN, Vinothkumar KR, Hirst J [Pubmed: 29395787] [DOI: 10.1016/j.str.2017.12.014] |
965.8 GB | 4.13 Å | |
2023-10-03 | Single particle cryo-EM dataset of mitochondrial respiratory complex I from Drosophila melanogaster [3082 multi-frame micrographs composed of 40 frames each in MRC format] | Agip AA, Chung I, Hirst J [Pubmed: 36622099] [DOI: 10.7554/eLife.84424] |
621.0 GB | 3.28 - 3.96 Å | |
2023-10-03 | Single particle cryo-EM dataset of mitochondrial complex I from Mus musculus inhibited by IACS-2858 - 1 [1957 multi-frame micrographs composed of 1 frames each in MRC format] | Chung I, Hirst J [Pubmed: 33990335] [DOI: 10.1126/sciadv.abg4000] |
312.6 GB | 3.04 Å | |
2023-10-03 | Single particle cryo-EM dataset of mitochondrial complex I from Mus musculus inhibited by IACS-2858 - 2 [571 multi-frame micrographs composed of 25 frames each in MRC format] | Chung I, Hirst J [Pubmed: 33990335] [DOI: 10.1126/sciadv.abg4000] |
95.9 GB | 3.04 Å | |
2023-10-03 | Single particle cryo-EM dataset of mitochondrial complex I from Mus musculus inhibited by IACS-2858 - 3 [1593 multi-frame micrographs composed of 1 frames each in MRC format] | Chung I, Hirst J [Pubmed: 33990335] [DOI: 10.1126/sciadv.abg4000] |
259.2 GB | 3.04 Å | |
2023-10-03 | Single-particle cryo-EM of APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD [25354 multi-frame micrographs composed of 39 frames each in TIFF format] | Bodrug T, Welsh KA, Bolhuis DL, Paulаkonis E, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG [Pubmed: 37735619] [DOI: 10.1038/s41594-023-01105-5] |
19.0 TB | 4.0 Å | |
2023-10-03 | Single particle cryo-EM dataset of mitochondrial respiratory complex I from Macaca mulatta [2523 multi-frame micrographs composed of 40 frames each in MRC format] | Agip ANA, Hirst J, Blaza JN [Pubmed: 30786232] [DOI: 10.1146/annurev-biophys-052118-115704] |
1.5 TB | 4.1 Å | |
2023-10-03 | Cryo electron tomography of Cytochalasin D-induced protrusions of Drosophila S2 cells treated with thapsigargin or MG132 [multiple data sets in TIFF and MRC formats] | Ventura Santos C, Carter AP [Pubmed: 37702953] [DOI: 10.15252/embr.202357264] |
107.6 GB | — | |
2023-10-03 | Single-particle Cryo-EM datasets of hydroxycarboxylic acid receptor signaling complexes [multiple data sets in TIFF format] | Suzuki S, Suzuki H, Fujiyoshi Y [Pubmed: 37736747] [DOI: 10.1038/s41467-023-41650-7] |
4.6 TB | 2.85 - 3.11 Å | |
2023-10-03 | Adaptive traits of cysts of the snow alga Sanguina nivaloides unveiled by 3D subcellular imaging [multiple data sets in TIFF format] | Ezzedine J, Uwizeye C, Si Larbi G, Villain G, Louwagie M, Schilling M, Hagenmuller P, Gallet B, Stewart A, Petroutsos D, Devime F, Salze P, Liger L, Jouhet J, Dumont M, Ravanel S, Amato A, Valay JG, Jouneau PH, Falconet D, Marechal E [DOI: 10.21203/rs.3.rs-3038444/v1] |
104.7 GB | — | |
2023-10-03 | In situ cryo-electron tomography of E. amylovora cells infected by the jumbo bacteriophage RAY [multiple data sets in TIFF format] | Prichard A, Lee J, Laughlin TG, Lee A, Thomas KP, Sy A, Spencer T, Asavavimol A, Cafferata A, Cameron M, Chiu N, Davydov D, Desai I, Diaz G, Guereca M, Hearst K, Huang L, Jacobs E, Johnson A, Kahn S, Koch R, Martinez A, Norquist M, Pau T, Prasad G, Saam K, Sandhu M, Sarabria AJ, Schumaker S, Sonin S, Sonin A, Uyeno A, Zhao A, Corbett K, Pogliano K, Meyer J, Grose JH, Villa E, Dutton R, Pogliano J [Pubmed: 36865095] [DOI: 10.1101/2023.02.24.529968] |
244.3 GB | 8.9 - 38.0 Å | |
2023-09-26 | Single particle cryo-EM dataset of human nucleolar and nuclear pre-60S assembly intermediates [multiple data sets in TIFF and MRCS formats] | Vanden Broeck A, Klinge S [Pubmed: 37410842] [DOI: 10.1126/science.adh3892] EMD-29104 EMD-29252 EMD-29105 EMD-29253 EMD-29106 EMD-29254 EMD-29107 EMD-29255 EMD-29108 EMD-29256 EMD-29109 EMD-29257 EMD-29110 EMD-29258 EMD-29111 EMD-29259 EMD-29112 EMD-29260 EMD-29113 EMD-29261 EMD-29114 EMD-29262 EMD-29115 EMD-29263 EMD-29130 EMD-29131 EMD-29132 EMD-29133 EMD-29134 EMD-29135 EMD-29136 EMD-29137 EMD-29138 EMD-29139 EMD-29140 EMD-29141 EMD-29142 EMD-29128 EMD-29129 EMD-29143 EMD-29144 EMD-29145 EMD-29146 EMD-29147 EMD-29148 EMD-29149 EMD-29150 EMD-29151 EMD-29152 EMD-29153 EMD-29154 EMD-29155 EMD-29156 EMD-29157 EMD-29158 EMD-29159 EMD-29160 EMD-29161 EMD-29162 EMD-29163 EMD-29164 EMD-29165 EMD-29166 EMD-29167 EMD-29168 EMD-29169 EMD-29170 EMD-29171 EMD-29173 EMD-29174 EMD-29175 EMD-29176 EMD-29177 EMD-29178 EMD-29179 EMD-29180 EMD-29181 EMD-29182 EMD-29183 EMD-29184 EMD-29185 EMD-29186 EMD-29187 EMD-29188 EMD-29189 EMD-29192 EMD-29194 EMD-29193 EMD-29116 EMD-29265 EMD-29117 EMD-29266 EMD-29118 EMD-29267 EMD-29119 EMD-29268 EMD-29120 EMD-29269 EMD-29121 EMD-29271 EMD-29122 EMD-29272 EMD-29123 EMD-29273 EMD-29124 EMD-29274 EMD-29125 EMD-29275 EMD-29126 EMD-29276 EMD-29127 EMD-29277 EMD-29195 EMD-29196 EMD-29197 EMD-29198 EMD-29199 EMD-29200 EMD-29201 EMD-29202 EMD-29204 EMD-29205 EMD-29206 |
140.5 TB | 2.33 - 3.75 Å | |
2023-09-25 | The potassium-selective channelrhodopsin HcKCR1 and HcKCR2 in lipid nanodisc [multiple data sets in TIFF format] | Tajima S, Kim YS, Fukuda M, Nakamura S, Yamashita K, Deisseroth K [Pubmed: 37652010] [DOI: 10.1016/j.cell.2023.08.009] |
4.1 TB | 2.53 - 2.66 Å |