EMPIAR-13635 - Cryo-electron microscopy structure of autoinhibited P-Rex2 [multiple data sets in EER format]

EMPIAR-13635

Cryo-electron microscopy structure of autoinhibited P-Rex2 [multiple data sets in EER format]

Publication:

The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1

Anderson LK, Marde R, Muma G, Nayak V, Phan C, Li S, Cash JN

The Journal of biological chemistry (2026)

PMID: 42248461

DOI: 10.1016/j.jbc.2026.113229

Related EMDB entry:

EMD-74550 EMD-74548 EMD-74547 EMD-74549

Deposited:

2026-04-14

Released:

2026-07-17

Last modified:

2026-07-17

Imageset size:

9.40 TB

Imageset DOI:

10.6019/EMPIAR-13635

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned movies of Autoinhibited P-Rex2 untilted part 1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4800

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

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2. Unaligned movies of Autoinhibited P-Rex2 untilted part 2

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3800

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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3. Unaligned movies of Autoinhibited P-Rex2 untilted part 3

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3469

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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4. Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4537

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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We recommend using rsync, aspera, globus, etc.

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5. Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 2

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3184

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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Citations

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

See all citations

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