EMPIAR-13635 - Cryo-electron microscopy structure of autoinhibited P-Rex2 [multiple data sets in EER format]

EMPIAR-13635

Cryo-electron microscopy structure of autoinhibited P-Rex2 [multiple data sets in EER format]

Publication:

The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1

Anderson LK, Marde R, Muma G, Nayak V, Phan C, Li S, Cash JN

The Journal of biological chemistry (2026)

PMID: 42248461

DOI: 10.1016/j.jbc.2026.113229

Related EMDB entry:

EMD-74550 EMD-74548 EMD-74547 EMD-74549

Deposited:

2026-04-14

Released:

2026-07-17

Last modified:

2026-07-17

Imageset size:

9.40 TB

Imageset DOI:

10.6019/EMPIAR-13635

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned movies of Autoinhibited P-Rex2 untilted part 1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4800

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

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2. Unaligned movies of Autoinhibited P-Rex2 untilted part 2

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3800

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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3. Unaligned movies of Autoinhibited P-Rex2 untilted part 3

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3469

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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4. Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4537

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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5. Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 2

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

3184

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.7296, 0.7296)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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Citations

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AlignPCA-2D: PCA-reduced Euclidean vector alignment for 2D classification in cryo-EM.

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prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)