EMPIAR-12995 - Cryo-EM structure of R-eLACCO2 in the lactate-bound state [8250 multi-frame micrographs composed of 48 frames each in TIFF format]

EMPIAR-12995

Cryo-EM structure of R-eLACCO2 in the lactate-bound state [8250 multi-frame micrographs composed of 48 frames each in TIFF format]

Publication:

A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics

Kamijo Y, Mächler P, Ness N, Vu CQ, Kusakizako T, Mannuthodikayil J, Ku Z, Boisvert M, Grebenik E, Miyazaki I, Hashizume R, Sato H, Liu R, Hori Y, Tomita T, Katayama T, Furube A, Caraveo G, Paquet M-E, Drobizhev M, Nureki O, Arai S, Brancaccio M, Campbell RE, Kleinfeld D, Nasu Y

Nature Communications 16 (2025)

PMID: N/A

DOI: 10.1038/s41467-025-64484-x

Related EMDB entry:

EMD-60263

Deposited:

2025-09-19

Released:

2025-10-30

Last modified:

2025-10-30

Imageset size:

1.71 TB

Imageset DOI:

10.6019/EMPIAR-12995

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of R-eLACCO2 in the lactate-bound state

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

8250

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.83, 0.83)

Details:

HT: 300 kV
Cs: 2.7 mm
Flux: 50 e/A2 over 48 frames

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Citations

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He L, Bartesaghi A. (2026)

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Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

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CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

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Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)