EMPIAR-10984 - Single particle cryo-EM dataset of mitochondrial respiratory complex I from Bos taurus in DDM [2370 multi-frame micrographs composed of 24 frames each in MRC format]

EMPIAR-10984

Single particle cryo-EM dataset of mitochondrial respiratory complex I from Bos taurus in DDM [2370 multi-frame micrographs composed of 24 frames each in MRC format]

Publication:

Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides

Bridges HR, Blaza JN, Yin Z, Chung I, Pollak MN, Hirst J

Science (New York, N.Y.) 379 (2023) 351-357

PMID: 36701435

DOI: 10.1126/science.ade3332

Related EMDB entry:

EMD-14126 EMD-14129 EMD-14130 EMD-14128 EMD-14131 EMD-14127

Deposited:

2022-03-17

Released:

2023-02-28

Last modified:

2023-03-01

Imageset size:

352.69 GB

Imageset DOI:

10.6019/EMPIAR-10984

Experimental metadata:

Download xml json

Compressed by PDBj:

Image formats and pixel types shown below are those of the original, non-compressed files.

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Contains:

micrographs - multiframe

Image Sets

1. Single particle cryo-EM dataset of mitochondrial respiratory complex I from Bos taurus in DDM

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

2370

Image size:

(3838, 3710)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(1.056, 1.056)

Details:

Gain corrected micrographs were imaged using a Gatan K2 summit camera in counting mode and GIF Quantum energy filter (20 eV slit width) on an FEI 300 keV Titan Krios microscope with a 100 μm objective aperture. 12s exposures captured in 24 frames and a total dose of 50 electrons Å-2.

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)