Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides

Bridges HR, Blaza JN, Yin Z, Chung I, Pollak MN, Hirst J

Science (New York, N.Y.) 379 (2023) 351-357

Movies (FoilHole*.mrc) in this entry were compressed to TIFF by EMPIAR Japan to save space and bandwidth.
The compression is lossless in that all pixel intensities remain exactly the same after decompression.
However, some metadata in the MRC header were lost.
The original files before compression are available from EMPIAR EBI.

Compression was carried out by separating (“un-normalizing”) the gain.
The details of the method are described in
https://relion.readthedocs.io/en/release-3.1/Reference/MovieCompression.html#gain-normalised-movies.

Please apply the gain reference (gain-reference.mrc) during processing.

Original size:   3,162,391,134 kilobytes
Compressed size:   369,820,650 kilobytes