EMPIAR-11902 - Engineered peptide-specific binder in complex with HLA-DR1/CLIP [21332 multi-frame micrographs composed of 1 frames each in EER format]

EMPIAR-11902

Engineered peptide-specific binder in complex with HLA-DR1/CLIP [21332 multi-frame micrographs composed of 1 frames each in EER format]

Publication:

A general system for targeting MHC class II-antigen complex via a single adaptable loop

Du H, Liu J, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg A, Julien JP, Mellins E, Garcia KC, Huang PS, Jude KM, Kassardjian A, Blackson W, Julien JP, Mellins ED

Nature biotechnology (2024)

PMID: 39672953

DOI: 10.1038/s41587-024-02466-y

Related EMDB entry:

EMD-43499

Deposited:

2024-01-24

Released:

2025-10-08

Last modified:

2025-10-08

Imageset size:

11.90 TB

Imageset DOI:

10.6019/EMPIAR-11902

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned movies of TRACeR-II-CLIP/MHC-II/DR1 complex

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

21332

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.743, 0.743)

Details:

template-picked particles in P60_S1_live_particles.cs

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)