EMPIAR-11902 - Engineered peptide-specific binder in complex with HLA-DR1/CLIP [21332 multi-frame micrographs composed of 1 frames each in EER format]

EMPIAR-11902

Engineered peptide-specific binder in complex with HLA-DR1/CLIP [21332 multi-frame micrographs composed of 1 frames each in EER format]

Publication:

A general system for targeting MHC class II-antigen complex via a single adaptable loop

Du H, Liu J, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg A, Julien JP, Mellins E, Garcia KC, Huang PS, Jude KM, Kassardjian A, Blackson W, Julien JP, Mellins ED

Nature biotechnology (2024)

PMID: 39672953

DOI: 10.1038/s41587-024-02466-y

Related EMDB entry:

EMD-43499

Deposited:

2024-01-24

Released:

2025-10-08

Last modified:

2025-10-08

Imageset size:

11.90 TB

Imageset DOI:

10.6019/EMPIAR-11902

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned movies of TRACeR-II-CLIP/MHC-II/DR1 complex

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

21332

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.743, 0.743)

Details:

template-picked particles in P60_S1_live_particles.cs

Files:

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Citations

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Ramírez-Aportela E, Zarrabeitia OL, Fonseca YC, Ceska T, Subramaniam S, Carazo JM, Sorzano COS. (2026)

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

Helical reconstruction of amyloids in cryoSPARC.

Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)

An unattended image-processing pipeline for on-the-fly quality assessment and 3D exploration in cryo-EM.

Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

CryoWriter: a robotic solution for improved Cryo-EM grid preparation.

Kv C, Ekundayo B, Di Fabrizio M, Mohammed I, Radecke J, Stahlberg H, Kube M. (2026)