EMPIAR-10924 - Apo C-terminal half of LRRK2 (I2020T) bound to microtubule [2379 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-10924

Apo C-terminal half of LRRK2 (I2020T) bound to microtubule [2379 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules

Snead DM, Matyszewski M, Dickey AM, Lin YX, Leschziner AE, Reck-Peterson SL

Nature structural & molecular biology 29 (2022) 1196-1207

PMID: 36510024

DOI: 10.1038/s41594-022-00863-y

Related EMDB entry:

EMD-25674

Deposited:

2022-01-08

Released:

2023-01-03

Last modified:

2023-01-03

Imageset size:

643.89 GB

Imageset DOI:

10.6019/EMPIAR-10924

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of apo microtubule bound C-terminus of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T)

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

2379

Image size:

(3710, 3838)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(1.16, 1.16)

Details:

Contains data collected from 2 grids (19dec14f and 20aug12b). Each folder contains its own gain reference with the "_norm.mrc" suffix found in the references folder. Blank dark references are also included but are not needed for correction. Gain correction in cryosparc should work with default settings, while for motioncor2, please flip the image and apply no rotation.
Total dose is 55 e/A-2

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Citations

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Protein Data Bank Japan News

[2026-06-10]

333件のPDBエントリーが新たに公開されました。（2026-06-10付）