EMPIAR-13078 - Cryo electron tomography of HIV-1 cores isolated by sedimentation through sucrose gradient [14 tilt series in TIFF format]

EMPIAR-13078

Cryo electron tomography of HIV-1 cores isolated by sedimentation through sucrose gradient [14 tilt series in TIFF format]

Publication:

Structural bases for integrase-RNA binding and retention of viral RNA within HIV-1 capsid cores

Singer RM, Zhen L, Rey SJ, Hope J, Chenavier F, Cook JN, Punch E, Smith J, Zhou Z, Maslen S, Masino L, Nans A, Skehel M, Taylor AI, Zanetti G, Zhang P, Perilla RJ, Engelman NA, Cherepanov P

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Related EMDB entry:

EMD-55409

Deposited:

2025-10-10

Released:

2025-12-12

Last modified:

2025-12-12

Imageset size:

11.03 GB

Imageset DOI:

10.6019/EMPIAR-13078

Experimental metadata:

Download xml json

Contains:

tilt series

Image Sets

1. Unaligned multi-frame micrographs from tilt series of HIV-1 cores, associated mdoc files, and gain reference

Category:

tilt series

Image format:

TIFF

No. of images or tilt series:

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.56, 1.56)

Details:

Each tilt image is comprised of 6 unaligned raw movie frames in TIFF format without gain correction. Gain reference is supplied as a separate file. Dose per tilt image is 2.54 e/A2 and total dose for each tilt series is 104 e/A2. Tilt azimuth is is 95 degrees.

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)