EMPIAR-13539 - An auto inhibitory loop in the MiDAC histone deacetylase complex [11093 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-13539

An auto inhibitory loop in the MiDAC histone deacetylase complex [11093 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome

Fairall L, Sirvydis K, Turnbull RE, Knottnerus SJ, Gonchar O, Muskett FW, Jukes-Jones R, van Brussel L, van de Geer E, van Gassen K, Badenhorst P, Johnson D, Terhal PA, van Hasselt PM, van Jaarsveld RH, Schwabe JW

Nature communications 16 (2025) 10472-10472

PMID: 41290615

DOI: 10.1038/s41467-025-65472-x

Related EMDB entry:

EMD-53564 EMD-53563 EMD-53565 EMD-53566 EMD-53567

Deposited:

2026-03-19

Released:

2026-06-04

Last modified:

2026-06-04

Imageset size:

2.27 TB

Imageset DOI:

10.6019/EMPIAR-13539

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Micrographs for MiDAC and nucleosome

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

11093

Image size:

(5760, 4092)

Pixel type:

SIGNED BYTE

Pixel spacing:

(0.835, 0.835)

Details:

---

Files:

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Citations

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