EMPIAR-12042 - Single particle cryo-EM analysis of cystic fibrosis transmembrane conductance regulator E1371Q mutant [10159 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12042

Single particle cryo-EM analysis of cystic fibrosis transmembrane conductance regulator E1371Q mutant [10159 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore

Gao X, Yeh HI, Yang Z, Fan C, Jiang F, Howard RJ, Lindahl E, Kappes JC, Hwang TC

Nature communications 15 (2024)

PMID: 39107303

DOI: 10.1038/s41467-024-50641-1

Related EMDB entry:

EMD-43011

Deposited:

2024-04-17

Released:

2024-08-26

Last modified:

2024-08-26

Imageset size:

5.02 TB

Imageset DOI:

10.6019/EMPIAR-12042

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of human cystic fibrosis transmembrane conductance regulator E1371Q mutant

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10159

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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