EMPIAR-12042 - Single particle cryo-EM analysis of cystic fibrosis transmembrane conductance regulator E1371Q mutant [10159 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12042

Single particle cryo-EM analysis of cystic fibrosis transmembrane conductance regulator E1371Q mutant [10159 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore

Gao X, Yeh HI, Yang Z, Fan C, Jiang F, Howard RJ, Lindahl E, Kappes JC, Hwang TC

Nature communications 15 (2024)

PMID: 39107303

DOI: 10.1038/s41467-024-50641-1

Related EMDB entry:

EMD-43011

Deposited:

2024-04-17

Released:

2024-08-26

Last modified:

2024-08-26

Imageset size:

5.02 TB

Imageset DOI:

10.6019/EMPIAR-12042

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of human cystic fibrosis transmembrane conductance regulator E1371Q mutant

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10159

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)