EMPIAR-11811 - Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain [19338 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11811

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain [19338 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain

Campbell EA, Small GI, Darst SA

Molecular Cell 83 (2023) 3921-3930

PMID: 37890482

DOI: 10.1016/j.molcel.2023.10.001

Related EMDB entry:

EMD-40707 EMD-40708

Deposited:

2023-11-28

Released:

2025-07-12

Last modified:

2025-07-12

Imageset size:

5.39 TB

Imageset DOI:

10.6019/EMPIAR-11811

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe micrographs

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

19338

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

Multiframe micrographs in TIFF format that were used as the basis for processing and determining a cryo-EM maps for the GDP-cap-i structure (EMD-40708, PDB-8SQK) and 20mer-SL structure (EMD-40707, PDB-8SQJ).

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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