EMPIAR-11811 - Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain [19338 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11811

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain [19338 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain

Campbell EA, Small GI, Darst SA

Molecular Cell 83 (2023) 3921-3930

PMID: 37890482

DOI: 10.1016/j.molcel.2023.10.001

Related EMDB entry:

EMD-40707 EMD-40708

Deposited:

2023-11-28

Released:

2025-07-12

Last modified:

2025-07-12

Imageset size:

5.39 TB

Imageset DOI:

10.6019/EMPIAR-11811

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe micrographs

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

19338

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

Multiframe micrographs in TIFF format that were used as the basis for processing and determining a cryo-EM maps for the GDP-cap-i structure (EMD-40708, PDB-8SQK) and 20mer-SL structure (EMD-40707, PDB-8SQJ).

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)