EMPIAR-12619 - Cryo-EM structure of human MPC in complex with UK5099 in LMNG [27126 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12619

Cryo-EM structure of human MPC in complex with UK5099 in LMNG [27126 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Structure of mitochondrial pyruvate carrier and its inhibition mechanism

He Z, Zhang J, Xu Y, Fine EJ, Suomivuori CM, Dror RO, Feng L

Nature (2025)

PMID: 40044865

DOI: 10.1038/s41586-025-08667-y

Related EMDB entry:

EMD-48442

Deposited:

2025-03-08

Released:

2026-07-07

Last modified:

2026-07-07

Imageset size:

10.41 TB

Imageset DOI:

10.6019/EMPIAR-12619

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. unaligned multi-frame micrographs of human MPC in complex with UK5099 in LMNG

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

27126

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.86, 0.86)

Details:

---

Files:

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Citations

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

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Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

See all citations

Protein Data Bank Japan News

[2026-07-08]

260 new PDB entries have been released on 2026-07-08.