EMPIAR-12492 - Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [10102 micrographs in MRC format]

EMPIAR-12492

Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [10102 micrographs in MRC format]

Publication:

Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4

Ekundayo B, Arullampalam P, Gerber CE, Hämmerli A, Guichard S, Boukenna M, Ross-Kaschitza D, Lochner M, Rougier J, Stahlberg H, Abriel H, Ni D

bioRxiv (2024)

DOI: 10.1101/2024.01.22.576650

Related EMDB entry:

EMD-19061

Deposited:

2024-12-12

Released:

2025-07-23

Last modified:

2025-07-23

Imageset size:

631.31 GB

Imageset DOI:

10.6019/EMPIAR-12492

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Dose weighted micrographs of SMA purified Trpm4

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

10102

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.726, 0.726)

Details:

Dose weighted micrographs in mrc file format- Trpm4 in SMA nanod

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

See all citations

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