EMPIAR-12492 - Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [10102 micrographs in MRC format]

EMPIAR-12492

Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [10102 micrographs in MRC format]

Publication:

Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4

Ekundayo B, Arullampalam P, Gerber CE, Hämmerli A, Guichard S, Boukenna M, Ross-Kaschitza D, Lochner M, Rougier J, Stahlberg H, Abriel H, Ni D

bioRxiv (2024)

DOI: 10.1101/2024.01.22.576650

Related EMDB entry:

EMD-19061

Deposited:

2024-12-12

Released:

2025-07-23

Last modified:

2025-07-23

Imageset size:

631.31 GB

Imageset DOI:

10.6019/EMPIAR-12492

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Dose weighted micrographs of SMA purified Trpm4

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

10102

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.726, 0.726)

Details:

Dose weighted micrographs in mrc file format- Trpm4 in SMA nanod

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)