EMPIAR-12474 - Cryo-EM structure of fedratinib-bound human SLC19A3 in inward-open state [5328 multi-frame micrographs composed of 45 frames each in TIFF format]

EMPIAR-12474

Cryo-EM structure of fedratinib-bound human SLC19A3 in inward-open state [5328 multi-frame micrographs composed of 45 frames each in TIFF format]

Publication:

Structural basis of thiamine transport and drug recognition by SLC19A3

Gabriel F, Spriestersbach L, Fuhrmann A, Jungnickel KEJ, Mostafavi S, Pardon E, Steyaert J, Löw C

Nature communications 15 (2024)

PMID: 39358356

DOI: 10.1038/s41467-024-52872-8

Related EMDB entry:

EMD-19752

Deposited:

2024-12-04

Released:

2026-07-07

Last modified:

2026-07-07

Imageset size:

4.58 TB

Imageset DOI:

10.6019/EMPIAR-12474

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Multiframe micrographs of fedratinib-bound human SLC19A3 in complex with Nb3.7

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

5328

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

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Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

See all citations

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[2026-07-08]

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