EMPIAR-11509 - In-tissue cryo electron tomography of App^NL-G-F amyloid plaques [23 tilt series in MRC format]

EMPIAR-11509

In-tissue cryo electron tomography of App^NL-G-F amyloid plaques [23 tilt series in MRC format]

Publication:

The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain

Leistner C, Wilkinson M, Burgess A, Lovatt M, Goodbody S, Xu Y, Deuchars S, Radford SE, Ranson NA, Frank RAW

Nature communications 14 (2023)

PMID: 37198197

DOI: 10.1038/s41467-023-38495-5

Related EMDB entry:

EMD-18301 EMD-16018

Deposited:

2023-04-14

Released:

2023-09-22

Last modified:

2023-09-22

Imageset size:

38.00 GB

Imageset DOI:

10.6019/EMPIAR-11509

Experimental metadata:

Download xml json

Contains:

tilt series

Image Sets

1. Summed, unaligned tilt series

Category:

tilt series

Image format:

MRC

No. of images or tilt series:

Image size:

(3710, 3838)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(3.421, 3.421)

Details:

Summed, unaligned tilt series from 23 tomograms, -60 to +60˚, 2˚ increments, 85.8˚ microscope rotation angle (hand unknown), ~1 e-/Å2 dose per tilt.
Corresponding CryoCLEM images are also supplied

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Citations

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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