EMPIAR-11066
Performing Correlative Light and Electron Microscopy to reveal the structural organization and location of alpha-synuclein aggregation hotspots inside the neuron. [multiple data sets in DM4 and TIFF formats]
Publication:

Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova E, Berezhnov AV, De S, Peddie C, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick A, Zanjani ZS, Angelova PR, Esteras N, Vinikurov A, Morris K, Jeacock K, Tosatto L, Little D, Gissen P, Clarke DJ, Kunath T, Collinson L, Klenerman D, Abramov AY, Horrocks MH, Gandhi S

bioRxiv (2022)

Related EMDB entry:
Deposited:
2022-06-01
Released:
2023-03-15
Last modified:
2023-03-15
Imageset size:
88.41 GB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - single frame
  • micrographs - multiframe
1. Unaligned TEM serial imaging data of a neuronal cell in culture (dish41)
Category:
micrographs - single frame
Image format:
DM4
No. of images or tilt series:
26
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(37.7, None)
Details:
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Files:
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2. Unaligned serial TEM imaging data of a neuronal cell in culture (dish42)
Category:
micrographs - single frame
Image format:
DM4
No. of images or tilt series:
30
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(37.7, None)
Details:
---
Files:
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3. Unaligned Serial TEM Imaging data of a neuronal cell in culture (Dish 43)
Category:
micrographs - single frame
Image format:
DM4
No. of images or tilt series:
7
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(37.7, None)
Details:
---
Files:
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4. FIB-SEM data set of a neuronal cell in culture (Dish 51)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1190
Image size:
(2337, 4347)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(50.0, 50.0)
Details:
---
Files:
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5. FIB-SEM data of a neuronal cell in culture (Dish 52)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1436
Image size:
(2000, 3430)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(50.0, 50.0)
Details:
---
Files:
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6. FIB-SEM data of a neuronal cell in culture (Dish 131)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1800
Image size:
(8152, 1949)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(50.0, 50.0)
Details:
---
Files:
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7. FIB-SEM data of a neuronal cell in culture (Dish 141)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1390
Image size:
(8393, 3439)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(50.0, 50.0)
Details:
---
Files:
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Files:
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