EMPIAR-10323 - Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy [1713 micrographs in MRC format]

EMPIAR-10323

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy [1713 micrographs in MRC format]

Publication:

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Böckmann A, Bousset L, Stahlberg H

eLife 8 (2019)

PMID: 31815671

DOI: 10.7554/eLife.48907

Related EMDB entry:

EMD-10307 EMD-10305

Deposited:

2019-09-23

Released:

2020-03-04

Last modified:

2020-08-13

Imageset size:

90.87 GB

Imageset DOI:

10.6019/EMPIAR-10323

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Aligned micrographs of alpha-synuclein fibrils

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

1713

Image size:

(3838, 3710)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.6556, 0.6556)

Details:

Micrographs were drift-corrected and dose-weighted using MotionCor2. Accumulated dose of 69 electrons per square Angstrom (10 second exposure, 50 frames)

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Citations

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CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

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ICECREAM: high-fidelity equivariant cryo-electron tomography.

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CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)