EMPIAR-10166 - human 26S proteasome bound to the chemotherapeutic Oprozomib [stack of 238631 particles in MRCS format]

EMPIAR-10166

human 26S proteasome bound to the chemotherapeutic Oprozomib [stack of 238631 particles in MRCS format]

Publication:

Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs

Haselbach D, Schrader J, Lambrecht F, Henneberg F, Chari A, Stark H

Nature communications 8 (2017) 15578-15586

PMID: 28541292

DOI: 10.1038/ncomms15578

Related EMDB entry:

EMD-4146

Deposited:

2018-03-21

Released:

2018-03-21

Last modified:

2018-03-21

Imageset size:

100.48 GB

Imageset DOI:

10.6019/EMPIAR-10166

Experimental metadata:

Download xml json

Contains:

picked particles - single frame - processed

Image Sets

1. Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib.

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

238631

Image size:

(336, 336)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(1.27, 1.27)

Details:

Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib. Total dose 40 electrons per Angstroem squared. Images are already inverted and normalized.

Files:

Archives and downloads the selected files into an uncompressed zip file.

Depending on the number and size of files to be downloaded, this can take an enormous amount of time. Also, this feature is unstable and may not work properly, and checksums of downloaded files are not verified.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

Browse All Files

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

Quick Links

Talks and Tutorials

EMPIAR Quick tour

Statistics

Publications

Re-use case study

EMPIAR in the news

Claim entries to your ORCiD

COVID-19 Data Portal

EMDB

PDBe

BioImage Archive

EMNavigator@PDBj

PDBj

RCSB@PDBj

EMDataResoruce@RCSB,EMDB,NCMI

Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

See all citations

Protein Data Bank Japan News

[2024-11-01]

A new portal integrating genome variants and protein structures has released

[2024-10-30]

294 new PDB entries have been released on 2024-10-30.

[2024-10-25]

PDBj luncheon seminar at APBJC 2024

[2024-10-17]

[wwPDB] The Nobel Prize in Chemistry 2024

[2024-10-16]

[wwPDB] wwPDB Data Release Policy on Public Preprint Archives