EMPIAR-10166 - human 26S proteasome bound to the chemotherapeutic Oprozomib [stack of 238631 particles in MRCS format]

EMPIAR-10166

human 26S proteasome bound to the chemotherapeutic Oprozomib [stack of 238631 particles in MRCS format]

Publication:

Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs

Haselbach D, Schrader J, Lambrecht F, Henneberg F, Chari A, Stark H

Nature communications 8 (2017) 15578-15586

PMID: 28541292

DOI: 10.1038/ncomms15578

Related EMDB entry:

EMD-4146

Deposited:

2018-03-21

Released:

2018-03-21

Last modified:

2018-03-21

Imageset size:

100.48 GB

Imageset DOI:

10.6019/EMPIAR-10166

Experimental metadata:

Download xml json

Contains:

picked particles - single frame - processed

Image Sets

1. Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib.

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

238631

Image size:

(336, 336)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(1.27, 1.27)

Details:

Particle stack of aligned, summed and dose weighted particle images from the human 26S proteasome bound to oprozomib. Total dose 40 electrons per Angstroem squared. Images are already inverted and normalized.

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Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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Citations

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CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM.

Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)

Structure of a RecT/Redβ family recombinase in complex with a duplex intermediate of DNA annealing.

Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)

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