EMPIAR-13500 - Filament of D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments [10156 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-13500

Filament of D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments [10156 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

How short peptides disassemble tau fibrils in Alzheimer's disease

Hou K, Ge P, Sawaya MR, Lutter L, Dolinsky JL, Yang Y, Jiang YX, Boyer DR, Cheng X, Pi J, Zhang J, Lu J, Abskharon R, Yang S, Yu Z, Feigon J, Eisenberg DS

Nature 644 (2025) 1020-1027

PMID: 40634605

DOI: 10.1038/s41586-025-09244-z

Related EMDB entry:

EMD-44183

Deposited:

2026-04-16

Released:

2026-04-26

Last modified:

2026-04-26

Imageset size:

4.91 TB

Imageset DOI:

10.6019/EMPIAR-13500

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Filament of D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10156

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.5335, 0.5335)

Details:

Dosage is 1.5 e-/A2 per frame. Use n22oct31f_31110844_01_8184x11520_norm_0.mrc for gain reference.

Files:

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