EMPIAR-12854 - Single particle cryo-EM dataset of CoREST complex bound to U2AF2 [12845 multi-frame micrographs composed of 1170 frames each in EER format]

EMPIAR-12854

Single particle cryo-EM dataset of CoREST complex bound to U2AF2 [12845 multi-frame micrographs composed of 1170 frames each in EER format]

Publication:

CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity

Fisher RJ, Park K, Lee K, Pinjusic K, Vanasse A, Ennis CS, Farokh P, Ficcaro S, Marto J, Jiang H, Nam E, Stransky S, Duke-Cohan J, Geethadevi A, Raabe E, Fiszbein A, Demehri S, Sidoli S, Hicks CW, Keskin DB, Wu CJ, Cole PA, Alani RM

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Related EMDB entry:

EMD-47265

Deposited:

2025-06-24

Released:

2025-11-19

Last modified:

2025-11-19

Imageset size:

7.04 TB

Imageset DOI:

10.6019/EMPIAR-12854

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of CoREST complex bound to U2AF2

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

12845

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.9, 0.9)

Details:

---

Files:

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Citations

AlignPCA-2D: PCA-reduced Euclidean vector alignment for 2D classification in cryo-EM.

Ramírez-Aportela E, Zarrabeitia OL, Fonseca YC, Ceska T, Subramaniam S, Carazo JM, Sorzano COS. (2026)

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

Helical reconstruction of amyloids in cryoSPARC.

Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)

An unattended image-processing pipeline for on-the-fly quality assessment and 3D exploration in cryo-EM.

Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

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