EMPIAR-12491 - Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [7199 micrographs in MRC format]

EMPIAR-12491

Cryo electron microscopy structure of human TRPM4 in SMA nanodisc [7199 micrographs in MRC format]

Publication:

Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4

Ekundayo B, Arullampalam P, Gerber CE, Hämmerli A, Guichard S, Boukenna M, Ross-Kaschitza D, Lochner M, Rougier J, Stahlberg H, Abriel H, Ni D

bioRxiv (---)

DOI: 10.1101/2024.01.22.576650

Related EMDB entry:

EMD-19057

Deposited:

2024-12-12

Released:

2025-07-23

Last modified:

2025-07-23

Imageset size:

449.94 GB

Imageset DOI:

10.6019/EMPIAR-12491

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Doseweighted micrographs in mrc file format- Trpm4 bound to NBA

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

7199

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.726, 0.726)

Details:

---

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)