EMPIAR-12265 - Full-length mouse 5-HT3A receptor in complex with serotonin, pre-activated and open-like [5771 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12265

Full-length mouse 5-HT3A receptor in complex with serotonin, pre-activated and open-like [5771 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Structural basis for partial agonism in 5-HT_3A receptors

Felt K, Stauffer M, Salas-Estrada L, Guzzo PR, Xie D, Huang J, Filizola M, Chakrapani S

Nature structural & molecular biology 31 (2024) 598-609

PMID: 38177669

DOI: 10.1038/s41594-023-01140-2

Related EMDB entry:

EMD-29418 EMD-29411

Deposited:

2024-09-03

Released:

2024-12-03

Last modified:

2024-12-03

Imageset size:

2.71 TB

Imageset DOI:

10.6019/EMPIAR-12265

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Raw movies, 5-HT3A + serotonin

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

5771

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.1, 1.1)

Details:

Raw movies of 5-HT3AR in complex with 100uM serotonin. Collected on titan krios and k3 camera. 81,000x magnification, super-resolution (import with 0.55 angstrom pixel size, 2x bin in Motioncorr), around 1 electron dose per frame. Dataset 1 of 2.

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