EMPIAR-11931 - Cryo electron structure of the ectodomain of Site-one protease without SPRING [6171 multi-frame micrographs composed of 1 frames each in EER format]

EMPIAR-11931

Cryo electron structure of the ectodomain of Site-one protease without SPRING [6171 multi-frame micrographs composed of 1 frames each in EER format]

Publication:

SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain

Hendrix S, Dartigue V, Hall H, Bawaria S, Kingma J, Bajaj B, Zelcer N, Kober DL

Nature communications 15 (2024)

PMID: 38977690

DOI: 10.1038/s41467-024-50068-8

Related EMDB entry:

EMD-42661

Deposited:

2024-03-02

Released:

2025-02-10

Last modified:

2025-03-17

Imageset size:

3.06 TB

Imageset DOI:

10.6019/EMPIAR-11931

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. eer format movies of site-one protease

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

6171

Image size:

(4096, 4096)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.738, 0.738)

Details:

Unprocessed micrographs and gain ref file for data collection corresponding to EMD-42661. The pixel size was 0.738 A. The nominal dose rate was 8.5 eps and the total dose was 55 e/A2. For processing, the movies were split into 50 frames.

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)