EMPIAR-11800 - Cryo-EM structure of apo-CAK [5805 multi-frame micrographs composed of 981 frames each in EER format]

EMPIAR-11800

Cryo-EM structure of apo-CAK [5805 multi-frame micrographs composed of 981 frames each in EER format]

Publication:

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Cushing VI, Koh AF, Feng J, Jurgaityte K, Bondke A, Kroll SHB, Barbazanges M, Scheiper B, Bahl AK, Barrett AGM, Ali S, Kotecha A, Greber BJ

Nature communications 15 (2024)

PMID: 38480681

DOI: 10.1038/s41467-024-46375-9

Related EMDB entry:

EMD-17523

Deposited:

2023-11-30

Released:

2024-05-16

Last modified:

2024-05-16

Imageset size:

2.34 TB

Imageset DOI:

10.6019/EMPIAR-11800

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. EER movies, apo-CAK, grid VC15-1

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5805

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.57, 0.57)

Details:

EER movies. The gain reference can be found in the top directory (data/NNP-K_220427_VC15-1/).

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)