EMPIAR-11470 - Unaligned cryo-EM micrographs of HCN4 channel bound to Ivabradine [31670 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-11470

Unaligned cryo-EM micrographs of HCN4 channel bound to Ivabradine [31670 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Structural determinants of ivabradine block of the open pore of HCN4

Saponaro A, Krumbach JH, Chaves-Sanjuan A, Sharifzadeh AS, Porro A, Castelli R, Hamacher K, Bolognesi M, DiFrancesco D, Clarke OB, Thiel G, Moroni A

Proceedings of the National Academy of Sciences of the United States of America 121 (2024)

PMID: 38917012

DOI: 10.1073/pnas.2402259121

Related EMDB entry:

EMD-16860

Deposited:

2023-03-16

Released:

2025-03-21

Last modified:

2025-03-21

Imageset size:

9.34 TB

Imageset DOI:

10.6019/EMPIAR-11470

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of HCN4 channel bound to Ivabradine

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

31670

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.42, 0.42)

Details:

The micrographs comes from two different data collection sessions and they are divided in two separated folders, each containing their own gain-reference file. The micrographs were recorded in super-resolution mode.

Files:

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Citations

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He L, Bartesaghi A. (2026)

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Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)