EMPIAR-11006
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809) [3191 multi-frame micrographs composed of 50 frames each in TIFF format]
Publication:

Mechanism of CFTR correction by type I folding correctors

Fiedorczuk K, Chen J

Cell 185 (2021) 158-168

PMID: 34995514

Related EMDB entry:
Deposited:
2022-02-16
Released:
2022-05-24
Last modified:
2022-05-31
Imageset size:
1.38 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
3191
Image size:
(7420, 7676)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.515, 0.515)
Details:
There are two datasets separated in subdirectories. Each set contains super-resolution, raw, uncorrected movies and gain references that have been flipped and rotated by 90 degrees for use. The super-resolution pixel size is 0.515 before binning.
Files:
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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)
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