EMPIAR-11006 - The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809) [3191 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11006

The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809) [3191 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Mechanism of CFTR correction by type I folding correctors

Fiedorczuk K, Chen J

Cell 185 (2021) 158-168

PMID: 34995514

DOI: 10.1016/j.cell.2021.12.009

Related EMDB entry:

EMD-25452

Deposited:

2022-02-16

Released:

2022-05-24

Last modified:

2022-05-31

Imageset size:

1.38 TB

Imageset DOI:

10.6019/EMPIAR-11006

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3191

Image size:

(7420, 7676)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.515, 0.515)

Details:

There are two datasets separated in subdirectories. Each set contains super-resolution, raw, uncorrected movies and gain references that have been flipped and rotated by 90 degrees for use. The super-resolution pixel size is 0.515 before binning.

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