EMPIAR-10896 - CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA [1381 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-10896

CryoEM of Mycobacterium tuberculosis WT RNAP holoenzyme/RbpA [1381 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA

eLife 7 (2018) 1-19

PMID: 29480804

DOI: 10.7554/elife.34823

Related EMDB entry:

EMD-7319

Deposited:

2021-12-10

Released:

2022-01-12

Last modified:

2022-02-25

Imageset size:

838.86 GB

Imageset DOI:

10.6019/EMPIAR-10896

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of M.tuberculosis RNAP holoenzyme with RbpA

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

1381

Image size:

(3710, 3838)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.5, 1.5)

Details:

---

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Citations

AlignPCA-2D: PCA-reduced Euclidean vector alignment for 2D classification in cryo-EM.

Ramírez-Aportela E, Zarrabeitia OL, Fonseca YC, Ceska T, Subramaniam S, Carazo JM, Sorzano COS. (2026)

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

Helical reconstruction of amyloids in cryoSPARC.

Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)

An unattended image-processing pipeline for on-the-fly quality assessment and 3D exploration in cryo-EM.

Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

CryoWriter: a robotic solution for improved Cryo-EM grid preparation.

Kv C, Ekundayo B, Di Fabrizio M, Mohammed I, Radecke J, Stahlberg H, Kube M. (2026)