EMPIAR-10871 - Cryo electron microscopy of recombinant, un-seeded hIAPP fibrils [6089 multi-frame micrographs composed of 30 frames each in MRC format]

EMPIAR-10871

Cryo electron microscopy of recombinant, un-seeded hIAPP fibrils [6089 multi-frame micrographs composed of 30 frames each in MRC format]

Publication:

Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils

Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS

Nature structural & molecular biology 27 (2020) 653-659

PMID: 32541896

DOI: 10.1038/s41594-020-0435-3

Related EMDB entry:

EMD-21410

Deposited:

2021-11-12

Released:

2021-11-29

Last modified:

2021-11-29

Imageset size:

1.90 TB

Imageset DOI:

10.6019/EMPIAR-10871

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned K2 movies of unseeded, recombinant hIAPP amyloid fibrils

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

6089

Image size:

(7676, 7420)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.535, 0.535)

Details:

Unaligned K2 movies, 1.45 e/A^2/frame. Gain is already flipped appropriately.

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)