EMPIAR-13309 - E. coli 70S ribosome with unmodified tRNAPro(GGG) bound to slippery P-site CCC-C codon and tRNAVal(UAC) in the A site [10949 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-13309

E. coli 70S ribosome with unmodified tRNAPro(GGG) bound to slippery P-site CCC-C codon and tRNAVal(UAC) in the A site [10949 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting

Kimbrough EM, Nguyen HA, Li H, Mattingly JM, Bailey NA, Ning W, Gamper H, Hou YM, Gonzalez RL, Dunham CM

Nature communications 16 (2025)

PMID: 40789848

DOI: 10.1038/s41467-025-62342-4

Related EMDB entry:

EMD-42495 EMD-42721

Deposited:

2026-02-16

Released:

2026-02-20

Last modified:

2026-02-20

Imageset size:

2.96 TB

Imageset DOI:

10.6019/EMPIAR-13309

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of E. coli 70S ribosomes with unmodified tRNAPro(GGG) bound to slippery P-site CCC-C codon and tRNAVal(UAC) in the A site

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10949

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.069, 1.069)

Details:

Raw TIFF movies with 50 frames each, pixel size of 1.069 angstroms per pixel, and total dose of 61.23 electrons per square angstrom.

Files:

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Citations

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

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Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

See all citations

Protein Data Bank Japan News

[2026-06-10]

333件のPDBエントリーが新たに公開されました。（2026-06-10付）