EMPIAR-13240 - Cryo-electron tomography of microtubules in undifferentiated induced pluripotent stem cells (iPSCs) [5 reconstructed volumes in MRC format]

EMPIAR-13240

Cryo-electron tomography of microtubules in undifferentiated induced pluripotent stem cells (iPSCs) [5 reconstructed volumes in MRC format]

Publication:

Microtubules in the axon are GDP-bound but adopt a stable GTP-like expanded state.

Zehr EA, Sun S, Sarbanes SL, Roll-Mecak A

Nature Structural & Molecular Biology (2026)

DOI: 10.1038/s41594-026-01787-7

Related EMDB entry:

EMD-70956

Deposited:

2025-12-08

Released:

2026-03-13

Last modified:

2026-04-15

Imageset size:

526.83 GB

Imageset DOI:

10.6019/EMPIAR-13240

Experimental metadata:

Download xml json

Contains:

reconstructed volumes

Image Sets

1. Reconstructed tomograms collected on undifferentiated iPSCs

Category:

reconstructed volumes

Image format:

MRC

No. of images or tilt series:

Image size:

(4092, 5760)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(2.656, 2.656)

Details:

These are reconstructed tomograms of undifferentiated induced pluripotent stem cells (iPSCs). The tomograms were reconstructed using AreTomo2 and binned 2×. Microtubule lattice spacing analysis was subsequently performed.

Files:

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Citations

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He L, Bartesaghi A. (2026)

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Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

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Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)