EMPIAR-13150 - Cryo electron microscopy of amyloid fibrils of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer’s disease tau fibrils [2169 multi-frame micrographs composed of 30 frames each in TIFF format]

EMPIAR-13150

Cryo electron microscopy of amyloid fibrils of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer’s disease tau fibrils [2169 multi-frame micrographs composed of 30 frames each in TIFF format]

Publication:

Structural evidence that RNA contributes to polymorphism of tau fibrils

Abskharon R, Jiang YX, Sawaya MR, Ge P, Zhang J, Boyer DR, Dolinsky JL, Pi J, Cascio D, Guo F, Eisenberg DS

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Related EMDB entry:

Deposited:

2025-04-16

Released:

2026-03-09

Last modified:

2026-03-09

Imageset size:

833.02 GB

Imageset DOI:

10.6019/EMPIAR-13150

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of amyloid fibrils of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer’s disease tau fibrils

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

2169

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

Dose = 1.2 e/A^2/frame
Total exposure = 36 e/A^2
Pixel size = 1.077

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)