EMPIAR-12500 - Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2 [10849 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-12500

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2 [10849 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating.

Li T, Dutka P, Erramilli SK, Nosol K, Pietrzak-Lichwa K, Li T, Hou J, Zhao M, Perozo E, Kossiakoff AA

Proceedings of the National Academy of Sciences of the United States of America 123 (2026)

PMID: 41701836

DOI: 10.1073/pnas.2512532123

Related EMDB entry:

EMD-41387 EMD-41390 EMD-41420 EMD-41386 EMD-41391 EMD-41385 EMD-41389 EMD-41388 EMD-41419 EMD-41421

Deposited:

2024-12-22

Released:

2026-02-04

Last modified:

2026-02-18

Imageset size:

3.32 TB

Imageset DOI:

10.6019/EMPIAR-12500

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs with CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10849

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.534, 0.534)

Details:

---

Files:

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Citations

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He L, Bartesaghi A. (2026)

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Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

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Jones HN, Deshmukh A, Pande K. (2026)

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ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)