EMPIAR-12450
Cryo-EM Structures of human LINE-1 ORF2p target-primed reverse transcription complex [multiple data sets in TIFF and MRCS formats]
Publication:

Structural mechanism of LINE-1 target-primed reverse transcription

Ghanim GE, Hu H, Boulanger J, Nguyen THD

Science (New York, N.Y.) (2025)

PMID: 40048554

Related EMDB entry:
Deposited:
2024-08-20
Released:
2025-04-07
Last modified:
2025-04-07
Imageset size:
5.12 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
  • picked particles - single frame - processed
1. Unaligned multi-frame micrographs of the human LINE-1 ORF2p TPRT complex
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
25374
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.955, 0.955)
Details:
These are movie files in TIFF format. Associated gain reference for the dataset is also included in TIFF format.
Files:
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2. Polished particle stack of the ORF2p TPRT complex consensus reconstruction (EMD-52070)
Category:
picked particles - single frame - processed
Image format:
MRCS
No. of images or tilt series:
680273
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.955, 0.955)
Details:
---
Files:
Loading...
3. Polished particle stack of the ORF2p TPRT complex with the fingers domain in a closed conformation (EMD-52071)
Category:
picked particles - single frame - processed
Image format:
MRCS
No. of images or tilt series:
185228
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.955, 0.955)
Details:
---
Files:
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4. Polished particle stack of the ORF2p TPRT complex with the fingers domain in an open conformation (EMD-52072)
Category:
picked particles - single frame - processed
Image format:
MRCS
No. of images or tilt series:
183579
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.955, 0.955)
Details:
---
Files:
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5. Polished particle stack of the ORF2p TPRT complex with the EN domain resolved (EMD-52073)
Category:
picked particles - single frame - processed
Image format:
MRCS
No. of images or tilt series:
121941
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.955, 0.955)
Details:
---
Files:
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