EMPIAR-12447 - Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril [5652 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12447

Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril [5652 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril

Sharma K, Banerjee S, Savran D, Rajes C, Wiese S, Girdhar A, Schwierz N, Lee C, Shorter J, Schmidt M, Guo L, Fändrich M

Journal of molecular biology 435 (2023)

PMID: 37481159

DOI: 10.1016/j.jmb.2023.168211

Related EMDB entry:

EMD-14739

Deposited:

2024-11-13

Released:

2025-06-02

Last modified:

2025-06-02

Imageset size:

928.00 GB

Imageset DOI:

10.6019/EMPIAR-12447

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe micrographs of full-length hnRNPA1 amyloid fibrils

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

5652

Image size:

(3838, 3710)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(1.04, 1.04)

Details:

Krios1 Quantum-K2
Cs 2.7
300kV EFTEM nanpprobe
x130k spot 8 beam size 620nm
c2=50 objective_aperture=100

GIF-K2 counting
12s exposure 40 frames
total dose at the sample 44.90e/A2
1 pixel = 1.04A
dose rate ~3 e/pix/s
defocus range -1.2 to -2.5

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Citations

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Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

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CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

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Protein Data Bank Japan News

[2026-06-10]

333件のPDBエントリーが新たに公開されました。（2026-06-10付）