EMPIAR-12410
Cryo-EM structures of SV2A in complex with antiepileptic drugs and botulinum neurotoxin A2 receptor-binding domain [multiple data sets in TIFF format]
Publication:

Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A

Yamagata A, Ito K, Suzuki T, Dohmae N, Terada T, Shirouzu M

Nature communications 15 (2024)

PMID: 38637505

Deposited:
2024-09-05
Released:
2025-06-26
Last modified:
2025-06-26
Imageset size:
6.62 TB
Imageset DOI:
Experimental metadata:
Download xml json
Deposited via PDBj
Contains:
  • micrographs - multiframe
1. SC2A-HcA2-LEV
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
6518
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.83, 0.83)
Details:
- 8JLC / EMD-36392
- 8JLE / EMD-36394
- 8JS8 / EMD-36616
- 8JLH / EMD-36397

- Microscope: FEI TITAN Krios
- Detector: Gatan K3 BIOQUANTUM
- Acceleration voltage (kV): 300
- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.
- Spherical aberration (Cs) : 2.7
- Nominal Defocus (μm): 0.8 - 2.0
- Average electron dose per image (e-/A2): 50.8
- Please use 'gain.mrc' as a gain reference without rotation and y-flipping.
Files:
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2. SV2-LEV
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
10001
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.83, 0.83)
Details:
- 8JLI / EMD-36398

- Microscope: FEI TITAN Krios
- Detector: Gatan K3 BIOQUANTUM
- Acceleration voltage (kV): 300
- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.
- Spherical aberration (Cs) : 2.7
- Nominal Defocus (μm): 0.8 - 2.0
- Average electron dose per image (e-/A2): 50.2
- Please use 'gain.mrc' as a gain reference without rotation and y-flipping.
Files:
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3. SV2A-HcA2
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
5930
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.83, 0.83)
Details:
- 8JLF / EMD-36395
- 8JLG / EMD-36396
- 8JS9 / EMD-36617

- Microscope: FEI TITAN Krios
- Detector: Gatan K3 BIOQUANTUM
- Acceleration voltage (kV): 300
- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.
- Spherical aberration (Cs) : 2.7
- Nominal Defocus (μm): 0.8 - 2.0
- Average electron dose per image (e-/A2): 50.0
- Please use 'gain.mrc' as a gain reference without rotation and y-flipping.
Files:
Loading...
4. SV2A-HcA2-BRV
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
6001
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.83, 0.83)
Details:
- 8K77 / EMD-36933, EMD-36934, EMD-36935

- Microscope: FEI TITAN Krios
- Detector: Gatan K3 BIOQUANTUM
- Acceleration voltage (kV): 300
- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.
- Spherical aberration (Cs) : 2.7
- Nominal Defocus (μm): 0.8 - 2.0
- Average electron dose per image (e-/A2): 50.0
- Please use 'gain.mrc' as a gain reference without rotation and y-flipping.
Files:
Loading...
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