EMPIAR-12306 - Cryo-EM Micrographs of Amyloid Fibrils of Mixed 0N4R and 0N3R Tau Seeded with Alzheimer's Disease Tau from Human Brain [7917 multi-frame micrographs composed of 45 frames each in TIFF format]

EMPIAR-12306

Cryo-EM Micrographs of Amyloid Fibrils of Mixed 0N4R and 0N3R Tau Seeded with Alzheimer's Disease Tau from Human Brain [7917 multi-frame micrographs composed of 45 frames each in TIFF format]

Publication:

Alzheimer's disease seeded tau forms paired helical filaments yet lacks seeding potential

Duan P, Dregni AJ, Xu H, Changolkar L, Lee VM, Lee EB, Hong M

The Journal of biological chemistry 300 (2024)

PMID: 39214304

DOI: 10.1016/j.jbc.2024.107730

Related EMDB entry:

EMD-45589

Deposited:

2024-09-24

Released:

2024-10-09

Last modified:

2024-10-09

Imageset size:

1.73 TB

Imageset DOI:

10.6019/EMPIAR-12306

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned Multi-frame Movies of Amyloid Fibrils of Mixed 0N4R and 0N3R tau seeded with AD Brain Tau

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

7917

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.06, 1.06)

Details:

Raw micrograph 45-frame movies, accumulating 45.73 electrons per squared Angstrom in 2.25 second exposures.

Files:

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Citations

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

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Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

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Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

See all citations

Protein Data Bank Japan News

[2026-06-17]

324件のPDBエントリーが新たに公開されました。（2026-06-17付）