EMPIAR-12182 - Single particle cryoelectron microscopy of Human astrovirus 1 spike in complex with neutralizing Fabs 3B4 and 3H4 [7235 multi-frame micrographs composed of 60 frames each in TIFF format]

EMPIAR-12182

Single particle cryoelectron microscopy of Human astrovirus 1 spike in complex with neutralizing Fabs 3B4 and 3H4 [7235 multi-frame micrographs composed of 60 frames each in TIFF format]

Publication:

Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization

Lanning S, Aguilar-Hernández N, Serrão VHB, López T, O'Rourke SM, Lentz A, Ricemeyer L, Espinosa R, López S, Arias CF, DuBois RM

Journal of virology (2025)

PMID: 39846739

DOI: 10.1128/jvi.01619-24

Related EMDB entry:

EMD-45427

Deposited:

2024-06-18

Released:

2025-10-10

Last modified:

2025-10-10

Imageset size:

26.37 TB

Imageset DOI:

10.6019/EMPIAR-12182

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Raw and processed data

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

7235

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

Raw and processed data collected at Krios G3i, 300 kV, 32.26 e/A2 using Gatan K3 Biocontinuum.

Files:

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Citations

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Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

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Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)